Both varieties contain CBD and THC (albeit at different levels), which are the two primary compounds in the Cannabis sativa plant. The Cannabis plant is also very diverse, as it can grow in many different forms. The most common types are Sativa and Indica, but there are more, with each type having dozens – if not hundreds – of different adaptations and different ratios of active compounds, also known as cannabinoids.
When pain is localized, topical products can be applied. These can be made using CBD-dominant cannabis as well as THC strains. Topicals affect the cells near application and through several layers of tissue but do not cross the blood-brain barrier and are, therefore, not psychoactive. These may be available as CBD oils, ointments, salves, or other forms, and with varying ratios of CBD and THC (a ratio of 1:1 is often recommended as ideal for skin application). The skin has the highest amount and concentration of CB2 receptors in the body.

Cannabidiol (CBD) is one of dozens of non-psychoactive cannabinoids found in the hemp plant. Cannabidiol, and all the other cannabinoids, were patented by the United States Government in 2003 as neuroprotectants and antioxidants (Patent No. 6,630,507). Cannabinoids are characterized by their ability to act on the cannabinoid receptors that are found throughout the body. CBD and other cannabinoids are naturally occurring compounds that display potent anti-inflammatory and pain-relieving properties. They can promote the body’s healthy regulation of the central nervous, immune, and endocannabinoid systems.

...with due respect, your experience Locsta is almost precisely what happened with my....chihuahua. Degenerative disc disease, excruciating pain, prednisone worked, but couldn't keep her on it..pain killers and muscle relaxants didn't help, really thought I would have to put her down. Chi bloggers suggested CBD; gave PetReleaf a shot--like you, literally within minutes I could see the difference, in days she was pain free and now is back in charge of our world. The real key here is that with my dog, there is zero, nada, chance that there was any placebo effect...

We’re proud to be among the few companies that provide lab analysis for their products. Results of our lab tests are visible for anyone who wants to see what Elixinol™ contains, and that is 18% CBD, along with all the synergistic cannabinoids in the original plant. We produce a wholesome extract, not an isolate nor a synthetic product, because our focus is on delivering a pure, highly qualitative CBD oil, and not a cheap product with zero benefits for your health.


After fighting the effects of thyroid cancerfor 12 years I wanted to die. Every day. Now, please understand that these were thoughts with no actions, I was just miserable in pain.After 1 week on the CBD oil, (5 drops under the toungue 2x per day) I am a different woman. I now have hope. Some of my emotional pain is presenting as physical pain, but IT'S LEAVING MY BODY.

One of the biggest stumbling blocks to widespread use of CBD is price. High-quality tinctures from brands like Floyd’s of Leadville and PlusCBD cost $35 or more; the bottles contain enough tincture to last about a month if you’re using an eyedropper’s worth per day. Prevail’s 2-ounce topical salve, which the company says should last most users between 30 and 45 days, costs $133. A one-month supply of a daily gel typically costs $30 to $60.


As it is an anti-inflammatory, you may find CBD skin-care products helpful when applied topically. Some research even points to its efficacy as an acne treatment, since it may limit inflammation in the sebum-producing glands that can lead to breakouts. If you're not having luck with traditional acne-fighting ingredients (like salicylic acid), it may be worth giving it a shot. 

In studying over 4,600 test subjects, researchers found that current cannabis users had fasting insulin levels that were up to 16 percent lower than their non-using counterparts, higher levels of HDL cholesterol that protects against diabetes, and 17 percent lower levels of insulin resistance. Respondents who had used cannabis in their lifetime but were not current users showed similar but less pronounced associations, indicating that the protective effect of cannabis fades with time.[180]
As a representative with 2 companies that have CBD on the market and as a person with intractable pain and multple painful problems wirth my spine I can say that cbd does not work for everyone. It does nothing for me or for my mil who has a cancer like growth impeding her ability to swallow and has undergone radiation to shrink it. Everyone has a chemistry that’s personal to them for some it helps but for many it does not. With that in mind it’s a 50/50 chance of it helping and until you come out your pocket you’ll never know. Buyer beware.

Oral CBD products with a ratio of 20:1 or higher and administered as drops, capsules, or edibles can be very effective in treating pain, especially the inflammatory type. Most discussions of treating pain with CBD suggest that finding the right dosage is critical. Always start with the micro dose to test sensitivity and go up as needed within the dosing range by body weight until symptoms subside. The micro to standard dose is usually recommended to treat pain, but patients need to carefully monitor their condition and experiment to find the right formula; 10–40 mg of CBD or CBD+THC together is usually enough.
Regarding your comment on CBD and colitis or inflammatory bowel disease. Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat do not sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues. When the balance tilts too far toward inflammation, inflammatory bowel disease can result. Now, researchers have found that a kind of tolerance-promoting immune cell appears that carry a specific bacterium in guts called Lactobacillus reuteri that is the normal part of the gut microbiome, and tryptophan, part of a protein-rich diet, soothes the inflamed gut because it increases the development of a population of immune cells that promote tolerance. Further, the bacterium needs tryptophan — one of the building blocks of proteins — to trigger the cells’ appearance, and the more tryptophan in the diet to feed the gut bacterium, Lactobacillus reuteri, the more of these immune cells there are.
Hemp oil cold pressed from hemp seeds grown in Canada. This hemp oil is also from an industrial hemp variety of Cannabis sativa which doesn’t require herbicides, pesticides, and fertilizers. Hemp oil is considered to be very nutritious with an ideal profile of omega 3 and 6, but the main purpose for it being in our blend is to have a base oil to emulsify the hemp extract into.
Back pain can be extremely debilitating, and it’s understandable if you want to steer clear of pharmaceutical painkillers in favor of something a little more natural. That’s what makes this Green Label Raw CBD Oil from Herbal Renewals so special. Available in three sizes, it’s a potent concentrate that gets to work in around fifteen minutes, and it can last for up to twelve hours, bringing real relief to back aches.
Yet when one looks at the industry more broadly, there is cause for concern. In February, as part of an investigation into the marketing claims of six hemp oil companies, the FDA analyzed 18 CBD products. What it found was disturbing: Many of these supposed CBD products were entirely lacking in CBD. Of the products tested, six contained no cannabinoids whatsoever. Another 11 contained less than 1 percent CBD. The product that tested highest in CBD, at 2.6 percent, was a capsule for dogs. In states that have legalized CBD, regulations can require CBD products to contain at least 5 percent CBD, more often 10 or 15 percent.

In short, Cannabidiol – or CBD – is a cannabis compound that has many therapeutic benefits. Usually extracted from the leaves and flowers of hemp plants – though marijuana can also be a source – CBD oil is then incorporated into an array of marketable products. These products vary from the most common, like sublingual oils and topical lotions, to the less common (think CBD lattes). Basically, if you can dream it, you can buy it.


The same terms could be applied to what's actually in CBD products. While some do contain CBD, others (often marketed as "CBD-rich hemp oil") may have barely any, Asquith says. And depending on state laws, they can include varying levels of THC too – a combination shown to have some benefits, but also drawbacks, of course, if you're not looking for a high. "People will play all these games with the numbers because the consumers aren't really educated in this space yet and it's easy to get taken advantage of," he says. "It's the milligrams of the actual CBD molecule that matter."
Preliminary research indicates that cannabidiol may reduce adverse effects of THC, particularly those causing intoxication and sedation, but only at high doses.[24] Safety studies of cannabidiol showed it is well-tolerated, but may cause tiredness, diarrhea, or changes in appetite as common adverse effects.[25] Epidiolex documentation lists sleepiness, insomnia and poor quality sleep, decreased appetite, diarrhea, and fatigue.[3]
On the federal level, several bills currently before Congress seek to change the way the government treats CBD. One such bill, the Compassionate Access Act, would exclude CBD from the classification of “marijuana” and remove both from the DEA’s list of Schedule I controlled substances. Rescheduling CBD in such a way would make research and cultivation of CBD much easier.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
This one isn’t for beginners. Make no mistake, this is strong stuff. You will only need the size of a grain of rice taken once or twice daily (the equivalent of roughly 4.1 milligrams of CBD) to feel the desired effects. With that kind of serving size, the three-gram tube will last you a few months of daily use, giving you plenty of CBD goodness. This product is also available in one-gram and ten-gram tubes, along with a six-pack of ten-gram tubes.
Heart disease is a growing problem today. In fact, it’s the leading cause of death in the U.S. A healthy diet and lifestyle is a top priority for heart health, but CBD oil can also help. According to research cannabidiol reduces artery blockage, reduces stress induced cardiovascular response, and can reduce blood pressure. It may also reduce cholesterol.
So Mechoulam called the Israeli national police and scored five kilos of confiscated Lebanese hashish. He and his research group isolated—and in some cases also synthesized—an array of substances, which he injected separately into rhesus monkeys. Only one had any observable effect. “Normally the rhesus monkey is quite an aggressive individual,” he says. But when injected with this compound, the monkeys became emphatically calm. “Sedated, I would say,” he recalls with a chuckle.

We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).


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“The need for enhanced bioavailability of the CBD phytonutrient is paramount”, adds Moriarity, “but tricky to accomplish without synthetic chemicals.” Most CBD products do not offer any bioavailability optimization, so 90 percent of the CBD is lost to first-pass effect, a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches systemic circulation.

CBD has been producing a whole lot of buzz in the health community of late – but perhaps not the kind of buzz you might expect from a cannabinoid. Since you’re reading this, you’ve probably heard of CBD and its many touted benefits. From chronic pain to mental health, CBD has the potential to alleviate an astonishing number of ailments. But like many, you might be fuzzy on the details. Consider this your primer on all things CBD.

Bored with your run-of-the-mill vape liquids? Want to try the alternative everyone’s talking about? This Silver Blend CBD e-Liquid from Alternate Vape is a game-changer. Individually crafted, incredibly flavorful, and packed with CBD, you’ll never vape the same again. Choose from one of six imaginative and tantalizing flavors to elevate your vaping experience to a whole new level.


For some, having more than trace amounts of Tetrahydrocannabinol (THC) might not be a big deal, but if you’re being drug tested at work, operating heavy machinery, or fall into a number of other categories, you may want to keep the THC to a bare minimum. In order to qualify as a legal hemp product, CBD oil must contain less than 0.03% THC. Look for CBD oil certified to have low levels of, or zero, THC in them. Many reputable sellers do offer products that have absolutely no THC in them at all, so if you are concerned about keeping even trace amounts of TCH out of your body, it is best to look for those products and sellers.

How do you take it? CBD products comes in a variety of forms, including tinctures, gel caps, and topical applications. One athlete-focused company, Floyd’s of Leadville, offers a protein recovery powder and a carb drink that contain CBD. (That’s Floyd as in Floyd Landis, the former professional cyclist who was stripped of his 2006 Tour de France title for failing a drug test and who helped to expose Lance Armstrong’s doping.) Another athlete-focused company, PurePower Botanicals, offers capsules that combine CBD with herbs and other purported medicinals, such as turmeric. PurePower says that the non-hemp-derived ingredients increase the effectiveness of the products’ CBD.


The manufacturer will probably give you a recommended dosage, but bear in mind that this isn’t set in stone. What you need to find is your own minimum effective dose. “Minimum effective dose” is a medical term which refers to the amount of a substance you need for the results you want, and above which, the substance doesn’t increase in effectiveness.
There are so many different CBD products out there to choose from, and it can be difficult to find the ones that are just right for you. To help you make an informed decision and enjoy CBD’s benefits to the fullest, we have put together several pages of invaluable information about CBD, its properties, its uses, and how YOU can best benefit from it.
We’re standing in a laboratory greenhouse on the campus of the University of Colorado Boulder looking at ten hemp plants that Kane recently procured for research purposes. They’re spindly, stalky little things, like gangling teenagers, a far cry from the lascivious crop that Hague had shown me. These plants, like nearly all hemp varieties, carry extremely low levels of THC.
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Cannabidiol (CBD) is one of dozens of non-psychoactive cannabinoids found in the hemp plant. Cannabidiol, and all the other cannabinoids, were patented by the United States Government in 2003 as neuroprotectants and antioxidants (Patent No. 6,630,507). Cannabinoids are characterized by their ability to act on the cannabinoid receptors that are found throughout the body. CBD and other cannabinoids are naturally occurring compounds that display potent anti-inflammatory and pain-relieving properties. They can promote the body’s healthy regulation of the central nervous, immune, and endocannabinoid systems.
A 2013 study that measured data from 4,652 participants on the effect of cannabis on metabolic systems compared non-users to current and former users. It found that current users had higher blood levels of high-density lipoprotein (HDL-C) or “good cholesterol.” The same year, an analysis of over seven hundred members of Canada’s Inuit community found that, on average, regular cannabis users had increased levels of HDL-C and slightly lower levels of LDL-C (“bad cholesterol”).

Hemp is a bioaccumulator, meaning it is capable of absorbing both the good and the bad from the air, water, and soil in which it’s grown. This makes it all the more important to know that your CBD oil comes from organically grown hemp that can be tracked to its US-grown source. The last thing buyers want is for their CBD oil to have accumulated toxic substances such as pesticides, herbicides, or heavy metals. For decades, farmers have used pesticides to protect crops against insects, disease, and fungi – and have used herbicides to control weeds – but we’ve known for quite some time that chemicals used to harm other species can also be harmful to our own species. That’s one big reason behind the global push to go organic. People are starting to prioritize organic crops, whether you’re talking about fruits, vegetables, grains, legumes, nuts, livestock feed – even textiles like cotton, wool, and flax.


Today, dozens of companies produce CBD in an array of forms. CBD can be inhaled through vape pens, applied in topical salves, ingested in edibles, or swallowed in oil-based tinctures. Oil has become the dominant CBD delivery method for kids with epilepsy, since it is easy to administer and ingest, and there is no shortage of it available for sale online. There are dozens of companies boasting names like Healthy Hemp Oil, Dose of Nature, and Natural Organic Solutions, each of them selling CBD products at prices ranging from trivial to dizzyingly steep. You don’t have to look hard to find them. If you have a PayPal account and $100 to spare, you could have a vial of hemp oil delivered to your doorstep.


Hi Lauren I've just started today with 250mg cbd oil. I'm starting low to see what happens. I've nerve damage across buttocks from a laminectomy. I've not been able to sit for 5 years. I've recently started with a muscle spasm in my left buttock and the muscle above is painful. It is only the first day, also tried a cbd night time tea as well. Do change in muscle pain so tight on my left hand side. How long before felt it starting to work please. I'm trying not to expect changes straightaway. I also take 1100mg gabapentin and 30mg amitriptyline and I hate both of them - they both can cause muscle tightness affecting the nerve. Thank you Lyn

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