Industrial hemp has low THC levels compared to marijuana specifically cultivated for personal psychoactive use. Whereas marijuana that can be smoked usually contains between five and ten percent THC, industrial hemp contains about one-tenth of that. In order to get a psychoactive effect, one would need to smoke ten or twelve hemp cigarettes over a very short period of time.
We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.
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Watch Out For: Companies that do not have test results or refuse to give them to customers. Also be wary of companies who only test one batch of finished product and then assume that all future batches will be the same – big mistake. Hemp is a product of nature and thus, no two batches will ever be identical – even in the most regulated environment. The company must provide you test results for the actual product you intend to purchase as well as the plant material used to make it – otherwise you are jeopardizing your safety and the medical efficacy of the product.
The words of these scientists convey the significance of the endocannabinoid system, first identified by Raphael Mechoulam in the mid-1990s and possibly one of the most important recent discoveries about the endogenous chemical transmitters involved in maintaining health. Endogenous (created naturally within the body) cannabinoids and their receptors are found not just in the brain but also in many organs as well as connective tissue, skin, glands, and immune cells. The list of CBD oil benefits and health concerns treatable by CBD is so long because these receptors are integral to so many bodily systems.
Still, for many, cannabis has become a tonic to dull pain, aid sleep, stimulate appetite, buffer life’s thumps and shocks. Pot’s champions say it peels back layers of stress. It’s also thought to be useful as, among other things, an analgesic, an antiemetic, a bronchodilator, and an anti-inflammatory. It’s even been found to help cure a bad case of the hiccups. Compounds in the plant, some scientists contend, may help the body regulate vital functions—such as protecting the brain against trauma, boosting the immune system, and aiding in “memory extinction” after catastrophic events.
Then came Reefer Madness. Marijuana, the Assassin of Youth. The Killer Weed. The Gateway Drug. For nearly 70 years the plant went into hiding, and medical research largely stopped. In 1970 the federal government made it even harder to study marijuana, classifying it as a Schedule I drug—a dangerous substance with no valid medical purpose and a high potential for abuse, in the same category as heroin. In America most people expanding knowledge about cannabis were by definition criminals.
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Cannabidiol (CBD), a non-psychoactive segment of the marijuana plant, has created huge enthusiasm among researchers and physicians.  CBD Oil applies its remedial effect on an atomic level is as yet being sorted out. Cannabidiol is a pleiotropic sedate in that it produces numerous impacts through various atomic pathways. CBD Oil acts through different receptor-free channels and by official with various non-cannabinoid receptors and particle channels.

If he had his way, what Mechoulam regards as the often irresponsible silliness of recreational pot culture would give way to an earnest and enthusiastic embrace of cannabis—but only as a medical substance to be strictly regulated and relentlessly researched. “Right now,” he complains, “people don’t know what they’re getting. For it to work in the medical world, it has to be quantitative. If you can’t count it, it’s not science.”
On the federal level, several bills currently before Congress seek to change the way the government treats CBD. One such bill, the Compassionate Access Act, would exclude CBD from the classification of “marijuana” and remove both from the DEA’s list of Schedule I controlled substances. Rescheduling CBD in such a way would make research and cultivation of CBD much easier.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.

Knowing how much CBD you’re taking can take a little math. Again, capsules are straightforward—the bottle will say how much CBD each one contains. For tinctures, you need to know the total amount of CBD in the container and the container’s size to calculate how much CBD is in each serving. I found 1-ounce tincture bottles, which contain roughly 30 servings, that ranged from containing 100 milligrams of CBD to 1,000.


Topical solutions also vary greatly in potency. For example, Prevail Botanical’s salve contains 1,000 milligrams of CBD in 2.2 ounces. Floyd’s of Leadville cream has 700 milligrams in a 30-gram (1.05 ounce) container. These deliver higher amounts of CBD than other topicals I tried, such as PlusCBD’s balm (100 milligrams in 1.3 ounces) and Medterra’s cream (750 milligrams in 3.4 ounces). Remember, more isn’t necessarily better.
Most acutely, the discomfort and stiffness I’d felt for months from a meniscus tear (confirmed by MRI) went away. The occasional twinges I had been getting on runs stopped. More significantly, what had been the tear’s near-constant presence in daily life, such as when getting up from sitting, has disappeared. For now I’ve postponed surgery on the tear. It’s impossible to know if CBD was the key factor in any of these changes. Still, at the end of the month I decided to keep taking CBD daily.
Juliana Birnbaum is trained as a cultural anthropologist and skilled in four languages and has lived and worked in the U.S., Europe, Japan, Nepal, Costa Rica and Brazil. In 2005 she founded Voices in Solidarity, an initiative that partnered with Ashaninka indigenous tribal leaders from the Brazilian Amazon to support the development of the Yorenka Ãtame community-led environmental educational center featured in Sustainable [R]evolution. She was the first graduate of the Cornerstone Doula School, one of the most rigorous natural birth programs in the U.S., focusing on a holistic model of care. She is engaged variously as writer, editor, teacher, midwife assistant and mother when not attempting new yoga poses or learning how to garden.

One of the most experienced practitioners in this field is Los Angeles physician Bonni Goldstein, who has used the compound to treat dozens of children with intractable epilepsy. She says about half of these patients have seen a significant drop in the number of seizures. “Used in the right way, with the right patient, CBD is extremely powerful,” she says.


I appreciate your efforts in writing this article & don’t mean to disparage you, but there’s so much information that goes into this discussion & people need to be prepared ahead of time. One very important note is to make sure that nothing in the CBD will be contraindicated with many prescription medications, especially for diabetes, hypertension, blood thinners & anti-platelets for example. If a company’s website says their formula is a “proprietary blend”, call before you buy, please!

I’m glad so many of you have been helped; I tried it upon recommendation from accupuncturist to help with anxiety & funny mood in the afternoon. The first night I woke up in the middle of the night and couldn’t get back to sleep, and had the most horrible constant headache for the 3 days after I took it (and I hadn’t had a headache in months). Also had the anxiety/funny mood all day long. And burning eyes.


* All CBD products offered on this site are produced in compliance with 21 U.S.C. § 802(16), 21 CFR 1308.11(d)(58 – 7350 Marijuana Extract),  and “Clarification of the New Drug Code (7350) for Marijuana Extract” published by the US Department of Justice, Drug Enforcement Administration, Diversion Control Division https://www.deadiversion.usdoj.gov/schedules/marijuana/m_extract_7350.html
In short, Cannabidiol – or CBD – is a cannabis compound that has many therapeutic benefits. Usually extracted from the leaves and flowers of hemp plants – though marijuana can also be a source – CBD oil is then incorporated into an array of marketable products. These products vary from the most common, like sublingual oils and topical lotions, to the less common (think CBD lattes). Basically, if you can dream it, you can buy it.
Hello. I have stage 4 thyroid, secondary lymphoma..And many other health issues.I use 50mg of cbd vapor oil. 5 drops with each use. Total equals 250mg, about hits per dose, three times a day. I'm also on subsys, which is fentanyl. Idk about anyone but myself, but it's helped me with pain, with sleep, and in general my moods. So I dint have anything negative to say. I just hope that with time, proper diet, low dose chemo, and some other herbal usage, that I can shirk some of the cancer eating at my body... Thanks and good luck to you all.
Dan Frey, a physical therapist in Portland, Maine, says that his patients report the most success using CBD to treat long-term trouble spots rather than acute injury sites. Frey, who doesn’t prescribe medication or supplements, says his conversations about CBD are initiated by patients. Many also tell Frey they find it helps with pain management, especially when used in conjunction with other treatments such as massage and a targeted strengthening and mobility program.
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.
I found I was too groggy during work hours if, on a typical day, I took CBD in the morning and at night. A dose of 25 milligrams an hour before going to bed, plus occasional topical use, has become my norm. The main exception is after an especially long or hard weekend run, when I have an additional 25 milligrams if I’m planning to mostly lounge about the house.
Similarly, though CBD oil is technically illegal on the federal level, it is sold freely online and in stores even here in New Jersey. Erica McBride, executive director of the National Hemp Association in Washington, said there have been instances in states where pot hasn't been legalized where CBD oil was confiscated at the post office or people possessing it were arrested, but it's “very rare.”
CBD also encourages the body to convert white fat to brown fat. White fat is the kind of fat we typically think of when we think about body fat. Brown fat is fat that is in small deposits that behaves differently than white fat. Brown fat is said to improve health by enhancing the bodies ability to burn white fat, create heat, and even regulate blood sugar.
Aside from being an antiseizure and antianxiety remedy, CBD is also known as an anti-inflammatory. Delivery for internal and muscular inflammation is recommended to be taken orally (sublingually, ingested, or vaporized) versus topically, which hasn't been backed by clinical studies. Doctors have said it could be outright impossible for CBD to permeate the layers of your skin (transdermally) to actually sink into your muscles. (See: Do CBD Pain-Relief Creams Really Work?)
Low CBD oil prices isn’t always a good thing, and it is something to watch out for as it’s our natural instinct to go for the lowest price possible. When discussing CBD oil, though, ones that are “abnormally” cheap will probably mean they have a low concentration (remember the Flaxseed analogy?). Prices of quality CBD should range around $50-$90 for a 300mg bottle.

Hemp is a bioaccumulator, meaning it is capable of absorbing both the good and the bad from the air, water, and soil in which it’s grown. This makes it all the more important to know that your CBD oil comes from organically grown hemp that can be tracked to its US-grown source. The last thing buyers want is for their CBD oil to have accumulated toxic substances such as pesticides, herbicides, or heavy metals. For decades, farmers have used pesticides to protect crops against insects, disease, and fungi – and have used herbicides to control weeds – but we’ve known for quite some time that chemicals used to harm other species can also be harmful to our own species. That’s one big reason behind the global push to go organic. People are starting to prioritize organic crops, whether you’re talking about fruits, vegetables, grains, legumes, nuts, livestock feed – even textiles like cotton, wool, and flax.
Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.
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Summary: Early research has found that CBD oil has the potential to reduce chronic pain, anxiety, depression and acne, and may help those overcoming addiction. Its anti-inflammatory properties may also play a role in lowering the risk of diabetes and cardiovascular disease. It has even shown anti-tumor effects and could be effective in inhibiting the progression of cancer and its related symptoms.

In addition to positively affecting the endocannabinoid system, CBD has been the focus of more than 23,000 published studies about cannabinoids in relation to various medical indications including anxiety, epilepsy, inflammation, cancer and chronic pain to name few. For a more comprehensive look at these and other studies, visit our medical research and education page.


Industrial hemp has low THC levels compared to marijuana specifically cultivated for personal psychoactive use. Whereas marijuana that can be smoked usually contains between five and ten percent THC, industrial hemp contains about one-tenth of that. In order to get a psychoactive effect, one would need to smoke ten or twelve hemp cigarettes over a very short period of time.
CBD capsules are all about convenience. They’re portable, discreet, easy to take, of a higher concentration, and have no taste whatsoever. Because of this, you’ll usually end up paying a little more per serving than some other CBD product types. If price is a concern, consider trying CBD concentrates. They’re the most pure form of CBD oil and are also the most cost-effective.
[387] S. Maione, F. Piscitelli, L. Gatta, D. Vita, L. De Petrocellis, E. Palazzo, V. de Novellis, and V. Di Marzo, “Non-psychoactive Cannabinoids Modulate the Descending Pathway of Antinociception in Anaesthetized Rats through Several Mechanisms of Action,” British Journal of Phramacology 162, no. 3 (2011): 584. doi:10.1111/j.1476-5381.2010.01063.x.
Hi Diane, how did you go on with the CBD oil please. If it worked how long before you saw any results. I'm scared of flaring everything. Nerve damage across buttocks from a surgeon who found the nerve stuck to the bulge during a laminectomy operation and prised it off. I haven't sat for 5 years and getting worse. A muscle in my buttock is now throbbing constantly and causing pain to the muscle above. I've only started taking it today but the muscle pain is still as painful. Does it take a while for it to work. Only started on low dose to see what happens. Thank you Lyn

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