I have had several neurological conditions like Bells Palsy three times, double vision, paralysis of left side of tongue. I have a lot of relief whenever I have pain by taking an inflamattory drug etoshine90 mg. Presently I have started taking Steroids for my facial palsy. The various pains I was having on the left side of neck, below the left ear, dizziness, pain around the head have subsided immidiately after the first dose of prendisolone 60 mg.I have read that CBD hemp oil can be useful for my condition of neurological and inflammation issues. My question is what concentrate (mg) of the oil should I take and for how long. Any brand that you may suggest that are available in the UK. Thank you.
When I came across the Nutiva Organic Hemp Oil it was so much less I started checking to find out what the difference was. I read the reviews and everyone was saying how much it helped. I decided to try it, not believing it was possible I might get some relief, but for the price what was there to lose, except pain. Well it's been six days since it arrived. I took one tablespoon that evening. Man, like drinking nutty oil, so I grabbed a piece of bread to get the taste out of my mouth. By morning I was feeling so much better. By that evening I noticed I didn't need a pain pill to help. By the third day I was able to sit up in bed without holding on to something. Today, the sixth day the pain in my legs, knees and hip joints is gone, but the clincher was the horrible pain in my lower back is almost gone. Swelling in my right hip is gone unless I get to active, then it becomes a dull ache. Best of all, I can sleep. I've been immobilized for several years, unable to do much for very long because I always had to sit back down. I was walking pitched forward to get around. Now I have to remember to straighten up. I not only look but I feel younger than my 72 years. No more pain pills for me. I'm so gitty over this I can't stop talking about it to my family and friends.
Then one day in 1963 a young organic chemist in Israel named Raphael Mechoulam, working at the Weizmann Institute of Science outside Tel Aviv, decided to peer into the plant’s chemical composition. It struck him as odd that even though morphine had been teased from opium in 1805 and cocaine from coca leaves in 1855, scientists had no idea what the principal psychoactive ingredient was in marijuana. “It was just a plant,” says Mechoulam, now 84. “It was a mess, a mélange of unidentified compounds.”

In the United States, cannabidiol is a Schedule I drug under the Controlled Substances Act.[60] This means that production, distribution, and possession of CBD is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[61] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[60][62]
Our full spectrum certified USDA organic CBD hemp oil for dogs and cats is extracted from our proprietary strain of hemp, PR-33. PR-33 is grown at our joint-venture certified USDA organic hemp farm in eastern Colorado and was selected because it’s cannabinoid profile was the most optimal for pets. In order for CBD oil for pets to be as beneficial as possible, every cannabinoid naturally found in the hemp plant must be present, THC included. This is because all of the cannabinoids in the hemp plant work together in what is called the “entourage effect,” this is why Pet Releaf never uses CBD isolate, CBD alone loses the majority if it’s medicinal benefits. The PR-33 strain is extremely high in the beneficial cannabinoid CBD and extremely low in THC at an almost undetectable level of 0.1%. PR-33 is a proprietary strain and will only ever be found in Pet Releaf products. We extract our CBD hemp oil using a super critical CO2 method, meaning we only use pressurized air to remove the CBD from the plant and never any toxic solvents or chemicals. Our CBD hemp oil for pets uses the flowers, leaves, and some seeds so that our products contain the full spectrum CBD that is extracted from the plant as well as the protein benefits of the seeds.
In the apparent rush to accept weed into the mainstream, to tax and regulate it, to legitimize and commodify it, important questions arise. What’s going on inside this plant? How does marijuana really affect our bodies and our brains? What might the chemicals in it tell us about how our neurological systems function? Could those chemicals lead us to beneficial new pharmaceuticals?
Dan Frey, a physical therapist in Portland, Maine, says that his patients report the most success using CBD to treat long-term trouble spots rather than acute injury sites. Frey, who doesn’t prescribe medication or supplements, says his conversations about CBD are initiated by patients. Many also tell Frey they find it helps with pain management, especially when used in conjunction with other treatments such as massage and a targeted strengthening and mobility program.
The lab also has studied how the chemicals in cannabis, as well as cannabinoids like the anandamide produced by our bodies, protect our brains against various types of insults, such as physical and emotional trauma. “Our brain needs to remember things, of course,” says Guzmán, “but it also needs to forget things—horrific things, unnecessary things. It’s much like the memory in your computer—you have to forget what is not necessary, just like you need to periodically delete old files. And you have to forget what is not good for your mental health—a war, a trauma, an aversive memory of some kind. The cannabinoid system is crucial in helping us push bad memories away.”
Pet Releaf is the number #1 and most trusted CBD for pets’ company in the world because we control our entire manufacturing process from seed to sale and from plant to pet. We spent years of research and development ensuring that every single part of our production process was safe for pets and that our final products were not only great for their health, but will always be something that we can wholeheartedly stand behind. From seed to sale, from plant to pet you can be confident that Pet Releaf CBD hemp oils for dogs and cats are the safest and most effective option for your pet.  
Possession or manufacture of cannabis and cannabis extracts is illegal in most jurisdictions. People caught with small amounts of extracts can face extremely harsh prison sentences. As of 2017 in some regions of the United States mandatory minimums of a year in jail still exist. However, it is widely produced in states where cannabis has been legalized.[1]
One of the most experienced practitioners in this field is Los Angeles physician Bonni Goldstein, who has used the compound to treat dozens of children with intractable epilepsy. She says about half of these patients have seen a significant drop in the number of seizures. “Used in the right way, with the right patient, CBD is extremely powerful,” she says.
We file past the curing rooms and down a hallway pulsating with pumps, fans, filters, generators, trimming machines. A forklift trundles by. Surveillance cameras capture everything, as young workers in medical scrubs scurry about, their faces lit with the pressure and promise of an unorthodox business that’s boomed beyond comprehension. Mindful has big plans to expand, building similar facilities in other states. “Pot is hot!” Hague says with a laugh that conveys amazement and exhaustion. “I’m blown away by what’s happening here every single day.”
Dan Frey, a physical therapist in Portland, Maine, says that his patients report the most success using CBD to treat long-term trouble spots rather than acute injury sites. Frey, who doesn’t prescribe medication or supplements, says his conversations about CBD are initiated by patients. Many also tell Frey they find it helps with pain management, especially when used in conjunction with other treatments such as massage and a targeted strengthening and mobility program.
Our hemp oil is cold pressed and cold filtered with no added preservatives or dyes. Each 15-millilitre serving (1 tablespoon) contains 10 grams of omega-3 and omega-6. The light, nutty taste is perfect drizzled over veggies, on pasta, or even on your popcorn for movie night. You can also add it to salad dressings, sauces, dips, and shakes. Use this light green oil as a substitute for other oils in recipes that aren’t heated above 300 °F (150 °C). Not recommended for frying.
In a study whose findings have not yet been published, he and a colleague, Daniel Friedman, found that patients receiving CBD in addition to their usual medicines had 39 percent fewer convulsive seizures than patients who remained on their normal drug regimen. Given that the study included only the most treatment-resistant patients, this is an “excellent response,” Devinsky says.
Hi Diane, how did you go on with the CBD oil please. If it worked how long before you saw any results. I'm scared of flaring everything. Nerve damage across buttocks from a surgeon who found the nerve stuck to the bulge during a laminectomy operation and prised it off. I haven't sat for 5 years and getting worse. A muscle in my buttock is now throbbing constantly and causing pain to the muscle above. I've only started taking it today but the muscle pain is still as painful. Does it take a while for it to work. Only started on low dose to see what happens. Thank you Lyn

Research shows that the effects of cannabis may help to protect the brain from the damage that is caused by a stroke. This is done by reducing the size of the area that was affected by the stroke. There has been research that has shown neuroprotective effects from cannabis that protects the brain in the case of other traumatic events, like concussions.


If you suffer from the constant anxiety during the night time hours, or suffer from insomnia or struggle from getting a restful, undisturbed sleep, then cannabis oil might be the solution for you. The cannabis oil works by relaxing the mind and body, and generating a lower energy level, it will be easier for you to get your heart rate down and clear your mind to allow for a long, restful sleep.
At Denver’s LivWell, which has an enormous indoor growing operation, workers remove marijuana leaves before the buds are trimmed, keeping the plants destined for medical use separate from those for recreational use. After Colorado legalized marijuana, thousands of young people from all over the world flocked to the state to participate in the multimillion-dollar business phenomenon that’s been called the Green Rush.

Guzmán leads me around his cramped lab—centrifuges, microscopes, beakers, petri dishes, a postdoc researcher in a white smock extracting tissue from a mouse corpse pinned under bright lights. It’s your typical bioresearch lab, except that everything is devoted to the effects of cannabis on the body and brain. The lab focuses not just on cancer but also on neurodegenerative diseases and on how cannabinoids affect early brain development. On this last topic the Guzmán group’s research is unequivocal: Mice born of mothers regularly given high doses of THC during pregnancy show pronounced problems. They’re uncoordinated, have difficulty with social interactions, and have a low anxiety threshold—they’re often paralyzed with fear at stimuli, such as a cat puppet placed near their cage, that don’t upset other juvenile mice.
After seasonal harvests of specific cultivars, these high-CBD hemp crops are put through a specialized solvent-free extraction process to yield a hemp oil that is naturally high in cannabidiol. This pure hemp extract is then tested for safety, quality, and cannabinoid content before being exported to our processing facilities in the United States. Importing any cannabis or hemp product into the United States is a complicated and serious task, so we leave nothing to chance before our high-CBD hemp oil makes its journey across the Atlantic Ocean.
Hello Roy,We will attempt to help you as much as possible.As you know CBD is a new treatment option so there are almost no scientific studies and very few case studies available. However as a general rule the best thing to do is just to start.We say this because everyones body metabolizes CBD at different rates. So the best way to find the proper dosage for you is just to start. The good news is that feeling sleepy is about the only side effect of overdosing CBD, so experimentation is pretty safe.What we recommend on our site is to start with 25mg of CBD taken as often as you need it throughout the day. If you find this works stick with it. If you find you need more, or are having to take it too many times during the day, then take more such as 50mg with each serving.Which oil should you use that will ship to the UK? We have reviewed all the top CBD oil products and have found Endoca to be the best and most powerful oil on the market. If you are going to use CBD hemp oil we recommend using raw CBD oil. This is the most natural and has the highest amount of plant constituents present which increases effectiveness.The best oil to start with is Endoca Raw Hemp Oil 2000mg. If taking 50mg a day this tube will last you 40 days. If you are taking 200mg a day you will need to purchase 3 tubes per month.Read the full review here: https://cbdoilreview.org/endoca-raw-hemp-oil-2000mg/Buy the product here: https://cbdoilreview.org/product/endoca-raw-hemp-oil-2000mg/Endoca ships to the UK from their European headquarters so you are good to go there. If you have any other questions please contact us using the form below or give us a call, we are happy to help!
I have/had ovarian/primary peritoneal cancer. I used thc/cbd oil pills I self made from the start. I am supposedly their “poster child”. I went thru with chemo and surgery. Oh that horror! But when I tried to tell two seperate doctors, the surgeon was all about it, and my oncologist threw a fit and said it was an anecdote. There are more than 100 studies at the NIH govt website.
The human body consists of an integral system known as the 'endocannabinoid system,' the duty of which is to regulate homeostasis, immunity function, pain response, balance and hormonal regulation. Issues arising in any of the mentioned mechanisms is corrected by this system so as to maintain the body's normal physiology. Cannabidiol tends to interact with the endocannabinoid receptors, and instead of binding to them like THC, it stimulates them. By doing so, it enhances the functioning of this regulatory complex. Cannabidiol's action on endocannabinoid receptors corrects several medical issues that may arise with its malfunctioning, such as, stress, fear, anxiety, etc.
Word of Caution: Although this list clearly shows that cannabis essential oil can be an effective remedy for many common health conditions, it is still a potent chemical substance extracted from a plant with psychotropic substances. Therefore, you should always be very careful while using such an essential oil, including the amount you use and the conditions under which you use it. Speak to a professional about mixing essential oils and present medications before adding any new elements to your health regimen. Also, the use of cannabis is restricted/banned in many countries, so consult a local health specialist before use.
Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain.[33] It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12.[14] Although currently classified as orphan receptors, these receptors are most closely related phylogeneticaly to the cannabinoid receptors.[14] In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist,[34] and this action may be involved in its antidepressant,[35][36] anxiolytic,[36][37] and neuroprotective effects.[38][39] It is an allosteric modulator of the μ- and δ-opioid receptors as well.[40] The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.[8]
Hemp oil contains some of the same terpenes as dried cannabis bud. Terpenes are the aroma molecules found in plants. Beta-caryophyllene (pepper) and myrcene (musk) are both been found in hemp oil.  According to recent research, beta-caryophyllene acts as a cannabinoid in the body. It engages some of the same cell sites as smoked cannabis. In particular, the terpene interacts with cell receptors that regulate the immune system.  Myrcene has been found to have antidepressant and anti-inflammatory effects. It also acts as an antioxidant and helps molecules move across cell membranes. The combination of essential fatty acids, vitamins, antioxidants and healing terpenes make hemp oil one powerful superfood.

What makes CBD so appealing is that it’s non-intoxicating, so it won’t get you high, though it “is technically psychoactive, because it can influence things like anxiety,” Jikomes said. Although much of the marketing blitz around CBD centers on the fact that you can take it without getting stoned, there isn’t much research looking at the effects of CBD when used in isolation, with a couple of exceptions. One is the use of CBD to treat seizures: CBD is the active ingredient in the only cannabis product that the Food and Drug Administration has signed off on — a drug called Epidiolex, which is approved for treating two rare forms of epilepsy. Animal models and a few human studies suggest that CBD can help with anxiety, but those are the only conditions with much research on CBD in isolation.
“THC products are more for the psychoactive effect, which may not be for everyone,” the Steamboat Springs, Colorado, resident says. “CBD use is for more health-minded people.” Collins says CBD products “are a big part of my daily routine,” and credits them with boosting his energy levels, speeding his recovery from long trail runs, and improving his sleep.
Back pain can be extremely debilitating, and it’s understandable if you want to steer clear of pharmaceutical painkillers in favor of something a little more natural. That’s what makes this Green Label Raw CBD Oil from Herbal Renewals so special. Available in three sizes, it’s a potent concentrate that gets to work in around fifteen minutes, and it can last for up to twelve hours, bringing real relief to back aches.
Jackson Leyden had always been a healthy kid; he practiced taekwondo, and he played lacrosse and baseball. But in 2011, a few months after his eighth birthday, he began having seizures several times a day. Many were brief, a half-minute of staring into space, but he also had severe episodes in which he would collapse, sometimes injuring himself. Over the next two years, he was hospitalized about 50 times, and he missed much of fourth and fifth grade.

I have/had ovarian/primary peritoneal cancer. I used thc/cbd oil pills I self made from the start. I am supposedly their “poster child”. I went thru with chemo and surgery. Oh that horror! But when I tried to tell two seperate doctors, the surgeon was all about it, and my oncologist threw a fit and said it was an anecdote. There are more than 100 studies at the NIH govt website.


In general, the preparation methods for unregulated cannabis oil are relatively simple. They do not entail highly specialised equipment, and use easily accessible solvents such as petroleum ether, naphtha, alcohol and olive oil. For this reason, people who have access to cannabis plant material, from either legal or illegal sources, may prepare it at home by themselves.
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I have sporadic back spasms for year I see a chiropractor monthly for maintenance (it help) and deal with daily Knee & hip joint pain due to my job (heavy mechanic/steel work with lots of walking). after reading all the great reviews on CBD oil I want to get off the daily ibuprofen regiment and try CBD oil. I would like to try it as a gel cap but would like some advise on dosage size. I also want to know how often I should take the CBD treatments. any and all advise is appreciated

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Medical Disclaimer: Statements in any video or written content on this site have not been evaluated by the FDA. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. Representations regarding the efficacy and safety of CBD oil have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. The material on this site is provided for informational purposes only and is not medical advice. Always consult your physician before beginning any supplement program.

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