Katie Wells, CTNC, MCHC, Founder and CEO of Wellness Mama, has a background in research, journalism, and nutrition. As a mom of six, she turned to research and took health into her own hands to find answers to her health problems. WellnessMama.com is the culmination of her thousands of hours of research and all posts are medically reviewed and verified by the Wellness Mama research team. Katie is also the author of the bestselling books The Wellness Mama Cookbook and The Wellness Mama 5-Step Lifestyle Detox.
Phillip Hague, the chief horticulturist at a Denver cannabis company called Mindful, sniffs the roots of a plant to check on their health. He’s grown cannabis most of his life and has traveled the world researching its many varieties. He’s interested in developing new strains with higher concentrations of marijuana’s lesser known compounds that appear to have medical uses. “Cannabis speaks to me,” he says.
The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.
As the brain ages, the creation of new neurons slows down significantly. In order to maintain brain health and prevent degenerative diseases, new cells need to be continuously created. A 2008 study showed that low doses of CBD- and THC-like cannabinoids encouraged the creation of new nerve cells in animal models, even in aging brains. CBD also benefits the brain by helping to prevent other nerve-related diseases like neuropathy and Alzheimer’s disease.
So Herrera, who's experienced her own share of pain due to a shoulder injury followed by a bout of Lyme disease, went to a local herb shop and bought a vial of the oil, which, by some definitions, is legal in all states if it doesn't contain more than 0.3 percent THC – the psychoactive component of cannabis. She began putting seven to nine drops under her tongue first thing most mornings – and was startled by the results. "It's changed my pain level, my anxiety level and my stress level," says Herrera, who already practiced yoga, meditated regularly, ate a healthy diet and tried conventional medical treatments for pain and mobility. "It was shocking," she says, because she thought her patients' reports were due to the placebo effect. "Right now," she adds, "I feel pretty amazing."
Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.
Selfhacked – you guys always put out such create content!! This was such a great scientific-based explanations, and concise, actionable ways to take advantage of the benefits of this specific cannabinoid. My 100-lb mastiff’s life was saved by using RxCBD dog treats, and I know someone else who’s grandfather has now enjoyed an additional year of life beyond docs’ projections, seemingly due to their ‘Ginger Snap cookies’. I’m an evangelist for #rxcbd, and #cbd in general (obviously). So glad it’s legal in all 50 states, and I appreciate seeing people as awesome as selfhacked shining light on it. Good on you guys!!
Low CBD oil prices isn’t always a good thing, and it is something to watch out for as it’s our natural instinct to go for the lowest price possible. When discussing CBD oil, though, ones that are “abnormally” cheap will probably mean they have a low concentration (remember the Flaxseed analogy?). Prices of quality CBD should range around $50-$90 for a 300mg bottle.
I have had several neurological conditions like Bells Palsy three times, double vision, paralysis of left side of tongue. I have a lot of relief whenever I have pain by taking an inflamattory drug etoshine90 mg. Presently I have started taking Steroids for my facial palsy. The various pains I was having on the left side of neck, below the left ear, dizziness, pain around the head have subsided immidiately after the first dose of prendisolone 60 mg.I have read that CBD hemp oil can be useful for my condition of neurological and inflammation issues. My question is what concentrate (mg) of the oil should I take and for how long. Any brand that you may suggest that are available in the UK. Thank you.
In early June, I met with Penny Pennington Howard, a mother of three, who lives in Carrollton, Texas, about 25 minutes outside of Dallas. Posted in the glass of her front door are two signs you can’t quite make out from the sidewalk: one asking visitors not to smoke, as oxygen treatments are in use; the other a yellow diamond informing guests this is the home of a special needs child. Penny welcomed me inside, out of the glare of the sun, and led me through her living room into her kitchen, where her kids were gathered for lunch. Seth, then eight months old, was plucking cereal off the tray of his highchair, while Lily, seven, was darting back and forth between the countertop and table. Harper, a blond five-year-old with hot pink toenails, was reclining in her “tomato chair,” a molded plastic seat with straps to help keep her steady.
Just like our website, there are many online retailers offering CBD oil for purchase. Alternatively, you can purchase CBD oil from brick and mortar stores too but there are not many to choose from. The good news is that you can expect a wider variety of options if you buy CBD oil online. You should simultaneously do the research to discover which brands produce the products to meet your needs.
But there’s a big difference between the two. Hemp seed oil has been pressed from hemp seed, and it’s great for a lot of things – it’s good for you, tastes great, and can be used in soap, paint – even as biodiesel fuel. However, hemp seed oil does not contain any concentration of cannabinoids at all, including CBD. So by all means, stock up at your local natural food store. Just don’t expect to reap the benefits of a true CBD oil when you cook with hemp seed oil.
After fighting the effects of thyroid cancerfor 12 years I wanted to die. Every day. Now, please understand that these were thoughts with no actions, I was just miserable in pain.After 1 week on the CBD oil, (5 drops under the toungue 2x per day) I am a different woman. I now have hope. Some of my emotional pain is presenting as physical pain, but IT'S LEAVING MY BODY.
 M. H. N. Chagas, A. L. Eckeli, A. W. Zuardi, M. A. Pena-Pereira, M. A. Sobreira-Neto, E. T. Sobreira, M. R. Camilo, M. M. Bergamaschi, C. H. Schenck, J. E. C. Hallak, V. Tumas, and J. A. S. Crippa, “Cannabidiol Can Improve Complex Sleep-Related Behaviours Associated with Rapid Eye Movement Sleep Behaviour Disorder in Parkinson’s Disease Patients: A Case Series,” Journal of Clinical Pharmacy and Therapeutics 39 (2014): 564–566. doi:10.1111/jcpt.12179.
Jackson Leyden had always been a healthy kid; he practiced taekwondo, and he played lacrosse and baseball. But in 2011, a few months after his eighth birthday, he began having seizures several times a day. Many were brief, a half-minute of staring into space, but he also had severe episodes in which he would collapse, sometimes injuring himself. Over the next two years, he was hospitalized about 50 times, and he missed much of fourth and fifth grade.
“This is a really powerful compound,” says Mikhail Kogan, the medical director of the George Washington University Center for Integrative Medicine. “I’ve seen it work for a lot of my patients.” He prescribes high-CBD strains of cannabis regularly for such illnesses as epilepsy, post-traumatic stress disorder, anxiety, autoimmune disorders, autism and insomnia.
Cannabinoids can be used along with opioid medications, and a number of studies have demonstrated that they can reduce the amount of opioids needed, lessen the buildup of tolerance, and reduce the severity of withdrawal. At least ten randomized, controlled trials on over one thousand patients have demonstrated efficacy of cannabinoids for neuropathic pain of various origins.
A 2007 study with the pharmaceutical 1:1 CBD:THC spray showed good results in helping patients with chronic pain sleep better. REM sleep behavior disorder (RBD) is characterized by the loss of complete muscle relaxation during REM sleep, associated with nightmares and physical activity during dreaming. Four patients in a case series treated with CBD in 2014 had prompt and substantial reduction in the frequency of RBD-related events without side effects. 
Carol, thanks for your long and detailed post, and the links. In your paragraph where you reference various effects, you write “cannabis” several times. There are several components of “cannabis”, THC is the more psychoactive component – and current varieties have been bred/engineered to have ever increasing concentrations of this. CBD is another component, which has different and in some cases opposing effects vs. THC. Are the statements you made about effects of “cannabis”, do they center on THC, consumption/use of the whole plant, or have they broken out a purified CBD product and tested the impacts of just that component. Earnest question.
There are thousands of unique varieties of hemp. The cultivars used for CBD oil contain significantly higher concentrations of CBD than others. Using these uniquely potent plants, it is possible to extract cannabis oil that contains significant levels of cannabidiol, as well as essential vitamins, minerals, fatty acids, terpenes, flavonoids, and other non-psychoactive cannabinoids.
Cannabinoids affect the transmission of pain signals from the affected region to the brain (ascending) and from the brain to the affected region (descending). A 2011 study showed that CBD and CBC stimulated descending pain-blocking pathways in the nervous system and caused analgesia by interacting with several target proteins involved in nociceptive control. Authors concluded that the cannabinoids “might represent useful therapeutic agents with multiple mechanisms of action.”  The following year, researchers reported that CBD significantly suppressed chronic inflammatory and neuropathic pain without causing apparent analgesic tolerance in animals.  And then in 2013, researchers concluded that chronic pain patients prescribed hydrocodone were less likely to take the painkiller if they used cannabis. 
This is a common question and misconception. As mentioned above, while they come from the same plant, they are different strains and CBD is harvested from the plants that contain no THC (or negligible levels). CBD is completely legal and is not considered a drug. Because of the often confused history of these plants, many manufacturers use “hemp oil” instead of the more controversial “CBD oil” in their marketing. CBD levels can vary drastically based on manufacturing, so it is important to find a high quality manufacturer with verified levels.
Of all the reasons that people use CBD today, pain is the most common. The same can be said of cannabis in general. In the United States, over seventy million people suffer from chronic pain, which is defined as experiencing over one hundred days per year of pain. Physicians differentiate between neuropathic (usually chronic) and nociceptive pains (usually time-limited), and cannabis works on most neuropathic and many nociceptive types of pain. A number of studies have demonstrated that the endocannabinoid system is both centrally and peripherally involved in the processing of pain signals. Most discussions of using CBD for pain treatment suggest that finding the right dosage is critical.
Hemp seed oil is used for various purposes and does not alone have the beneficial ingredients of CBD oil. So when you buy hemp oil hoping to get the CBD benefits, pay close attention to the CBD concentration. One of the best ways to ensure you are buying a good source of CBD oil is to find a website that publishes reviews of products. The site must provide objective reviews of dozens of products, not just two or three that may even be produced by the company that owns the site. Also asking peers or persons facing similar medical difficulties may be a good way to find the best place to buy CBD products.
While THC affects your brain’s endocannabinoid receptors (resulting in the high), CBD does not attach directly to the receptors. Instead, it influences your body into using its own natural supply of cannabinoids more effectively. That is to say, it can inhibit or activate compounds in the ECS, which in turn can impact the amount of pain you feel or limit inflammation in the brain and nervous system.
At Elixinol, we’re not selling magic potion in a bottle. Our CBD oil is not a miraculous cure that will make illnesses go away overnight. We don’t sell drugs, and we’re not producing medical marijuana. What we do offer you is a powerful dietary supplement with an impressive concentration of CBD, a product that is safe and is obtained through a technology that allows it to retain all the nutrients found in the original plant.
Most acutely, the discomfort and stiffness I’d felt for months from a meniscus tear (confirmed by MRI) went away. The occasional twinges I had been getting on runs stopped. More significantly, what had been the tear’s near-constant presence in daily life, such as when getting up from sitting, has disappeared. For now I’ve postponed surgery on the tear. It’s impossible to know if CBD was the key factor in any of these changes. Still, at the end of the month I decided to keep taking CBD daily.
In relation to sleep apnea, a 2002 animal study observed the ability of THC to restore respiratory stability by modulating serotonin signaling and reducing spontaneous sleep-disordered breathing. In 2013 a trial using the pharmaceutical drug dronabinol, a synthetic THC mimic, noted improvements in fifteen out of seventeen study participants following twenty-one days of treatment.
CBD may help reduces REM behavior disorder in people with Parkinson’s disease. REM behavior disorder is a condition that causes people to act out physically during dreaming and REM sleep. Typically, during REM, the body is largely paralyzed, a state known as REM atonia. This immobilization keeps sleepers from reacting physically to their dreams. In REM behavior disorder, this paralysis doesn’t occur, leaving people free to move—which can lead to disruptive sleep and to injuring themselves or their sleeping partners. Cannabis may also work to reduce pain and improve sleep quality in people with Parkinson’s disease.
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