For most people with epilepsy, diagnosis sets off a gauntlet of trial-and-error attempts to find the right medication. The process is tortuous, with seizures alternately dying down and flaring up while side effects— fatigue, nausea, liver damage, and more—develop without warning. This is partly due to the fact that “epilepsy” is actually a broad category that includes a number of distinct seizure disorders. About 30 medications approved by the U.S. Food and Drug Administration are currently used to treat these conditions, and when a person first begins having seizures, there is often much tinkering with combinations and dosages. I spent years battling side effects like vomiting, dizziness, drowsiness, and severe headaches, which were alleviated only by yet another prescription medication. Parents who endure enough sleepless nights caring for a sick child can become desperate for a cure.
Herrera and her patients aren't the only ones doling out rave reviews for CBD oil, which can be found online and in cannabis dispensaries, as well as in some grocery stores and even as an optional add-in alongside protein powder at your local juice chain. The oil has been riding the coattails of the growing legal cannabis industry, with one industry expert, Matt Karnes, telling Forbes in 2016 that he expected CBD products to become an almost $3 billion market by 2021.
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.
The skin has the highest amount and concentration of CB2 receptors in the body. When applied topically as an infused lotion, serum, oil, or salve, the antioxidant (a more powerful antioxidant than vitamins E and C) in CBD oil has many benefits and can repair damage from free radicals like UV rays and environmental pollutants. Cannabinoid receptors can be found in the skin and seem to be connected to the regulation of oil production in the sebaceous glands. Cannabis-based topical products are being developed to treat related issues from acne to psoriasis and can promote faster healing of damaged skin. In fact, historical documents show that cannabis preparations have been used for wound healing in both animals and people in a range of cultures spanning the globe and going back thousands of years. The use of concentrated cannabis and CBD oils to benefit and treat skin cancer is gaining popularity with a number of well-documented cases of people curing both melanoma and carcinoma-type skin cancers with the topical application of CBD and THC products. Best known is the case of Rick Simpson, who cured his basal cell carcinoma with cannabis oil and now has a widely distributed line of products. Cannabis applied topically is not psychoactive.
A 2012 research review assessed a number of international studies and concluded that CBD has been shown to reduce anxiety, and in particular social anxiety, in multiple studies and called for more clinical trials. Two years later, researchers in an animal study related to stress and the endocannabinoid system wrote that augmentation of the endocannabinoid system might be an effective strategy to mitigate behavioral and physical consequences of stress.
So Herrera, who's experienced her own share of pain due to a shoulder injury followed by a bout of Lyme disease, went to a local herb shop and bought a vial of the oil, which, by some definitions, is legal in all states if it doesn't contain more than 0.3 percent THC – the psychoactive component of cannabis. She began putting seven to nine drops under her tongue first thing most mornings – and was startled by the results. "It's changed my pain level, my anxiety level and my stress level," says Herrera, who already practiced yoga, meditated regularly, ate a healthy diet and tried conventional medical treatments for pain and mobility. "It was shocking," she says, because she thought her patients' reports were due to the placebo effect. "Right now," she adds, "I feel pretty amazing."
While it’s surely a good thing to make CBD oil easily available for people all over the world, the increasing popularity of products rich in cannabinoids has a not so pleasant side effect. Driven by the desire to explore this business opportunity and get the most of it, producers use misleading marketing and deceptive advertising to increase profits.
If you’re just diving into the world of CBD, we recommend a starting serving size of two to three milligrams. From there, you can work your way up to 100 or even 200 milligrams, after you’ve taken the time to gradually observe how CBD affects your body and mind. Remember, you cannot overdose on CBD, and there are no reported side effects from using high concentrations.
Cannabidiol, also known as CBD oil, is one of the fastest growing – in popularity – health supplements in America. The industry is exploding because people are learning about the beneficial properties of the substance. The government doesn’t regulate CBD oil for sale like it regulates pharmaceutical products, so it is understandable that some may be concerned about finding legitimate CBD oil, or hemp oil for sale.
The seizures started in May 2013 when she was six months old. Infantile spasms, they were called. It looked like a startle reflex—her arms rigid at her side, her face a frozen mask of fear, her eyes fluttering from side to side. Addelyn Patrick’s little brain raced and surged, as though an electromagnetic storm were sweeping through it. “It’s your worst possible nightmare,” her mother, Meagan, says. “Just awful, awful, awful to watch your child in pain, in fear, and there’s nothing you can do to stop it.”
It’s a truism to state that pain is an inevitable part of life. And it’s true that we all, from time to time, experience pain that is short-lived and treatable. But those who deal with chronic pain know the debilitating, life-sucking reality of this condition. And traditional medications often come with long lists of side effects which can be as debilitating as the pain itself.
Hague joined Colorado’s green revolution nearly at the beginning. When the U.S. Justice Department announced in 2009 that it would not focus on prosecuting people who complied with state medical marijuana laws, he looked at his wife and said, “We’re moving to Denver.” Now he runs one of the world’s most prominent “grows,” where more than 20,000 cannabis plants thrive.
Medical reviews published in 2017 and 2018 incorporating numerous clinical trials concluded that cannabidiol is an effective treatment for certain types of childhood epilepsy. An orally administered cannabidiol solution (brand name Epidiolex) was approved by the US Food and Drug Administration in June 2018 as a treatment for two rare forms of childhood epilepsy, Lennox-Gastaut syndrome and Dravet syndrome.
All of this makes CBD remarkably difficult for even the most dedicated health care providers to manage safely. Dr. Kelly Knupp, an associate professor of pediatrics and neurology at the University of Colorado, and the director of the Dravet Syndrome program at Children’s Hospital Colorado, said families of epileptic children have tried to bring CBD oils to the hospital for testing. “They’re just concerned that they don’t know exactly who’s growing [the hemp],” Knupp said. “They know it’s not being regulated.” But because CBD is a Schedule I controlled substance, high-tech, regulated laboratories, like those at the University of Colorado, can’t accept, store, or test CBD oils, lest they risk prosecution. “There is no such lab that can take that product,” Knupp said, which leaves any testing up to the unregulated testing centers that cater to the cannabis industry.
As the brain ages, the creation of new neurons slows down significantly. In order to maintain brain health and prevent degenerative diseases, new cells need to be continuously created. A 2008 study showed that low doses of CBD- and THC-like cannabinoids encouraged the creation of new nerve cells in animal models, even in aging brains. CBD also benefits the brain by helping to prevent other nerve-related diseases like neuropathy and Alzheimer’s disease.
Conversely, to preserve most of the plant’s trichromes – these are the cannabinoids, terpenes, and flavonoids – look for Supercritical (or subcritical) CO2 extraction. This method uses carbon dioxide under high pressure and extremely low temperatures to isolate, preserve, and maintain the purity of the medicinal oil. While this method is more expensive and involves complex equipment and expertise, it ensures quality.
Growing and producing CBD oil made from hemp may soon become fully legal. Lawmakers are working to finalize a 2018 Farm Bill sponsored by Sen. Mitch McConnell that removes hemp from the controlled substances list, allowing it to be grown legally on a large scale. Negotiators are hoping for a completed report this month and a vote on the bill by year's end.
“It can affect everything from emotion to pain to appetite to energy metabolism to brain function to even the immune system and inflammation,” says Hector Lopez, M.D., a consultant to PlusCBD Oil, one of the top-selling brands. “When you have a system that cross talks with all those pathways, then there are very few things the endocannabinoid system does not influence.”
Back pain can be extremely debilitating, and it’s understandable if you want to steer clear of pharmaceutical painkillers in favor of something a little more natural. That’s what makes this Green Label Raw CBD Oil from Herbal Renewals so special. Available in three sizes, it’s a potent concentrate that gets to work in around fifteen minutes, and it can last for up to twelve hours, bringing real relief to back aches.
Both varieties contain CBD and THC (albeit at different levels), which are the two primary compounds in the Cannabis sativa plant. The Cannabis plant is also very diverse, as it can grow in many different forms. The most common types are Sativa and Indica, but there are more, with each type having dozens – if not hundreds – of different adaptations and different ratios of active compounds, also known as cannabinoids.
Combining the powerful properties of CBD with a unique mix of herbs and other all-natural ingredients, this Hemp Signature Blend from Bluebird Botanicals offers real and effective relief from the symptoms of inflammation. Designed to support your body and soothe your joints, this is CBD oil redefined. The fascinating inclusion of frankincense carteri, black cumin seed, cold-pressed oil, and rosemary extract marks this out as something special.
By popular demand, we have also begun to carry several, high quality CBD pet products as well. For general purpose applications, we carry several, tasty tincture and oral spray options that are highly effective. Likewise, Pharma CBD capsules provide CBD purity via capsular ingestion. In addition, we have partnered with Therabis, the quality CBD maker of “Stop the Itch” and “Calm and Quiet”, the pet lovers’ ultimate go-to’s. Find these products by browsing our exclusive online inventory.
Support for legalization has steadily grown over the last several years. Today, medical marijuana is legal in 23 states and the District of Columbia. And even federal officials have begun to soften their stances. Last fall, outgoing Attorney General Eric Holder signaled his support for removing marijuana from the list of Schedule I narcotics. “I think it’s certainly a question we need to ask ourselves, whether or not marijuana is as serious of a drug as heroin,” Holder said. This summer, Chuck Rosenberg, the acting administrator of the U.S. Drug Enforcement Administration, acknowledged that marijuana is not as dangerous as other Schedule I drugs and announced his agents would not be prioritizing marijuana enforcement. Still, as long as marijuana remains illegal under federal law, the haphazard system in which it is studied, produced, and distributed will remain, and Americans will not be able to take full advantage of its medicinal properties.
When pain is localized, topical products can be applied. These can be made using CBD-dominant cannabis as well as THC strains. Topicals affect the cells near application and through several layers of tissue but do not cross the blood-brain barrier and are, therefore, not psychoactive. These may be available as CBD oils, ointments, salves, or other forms, and with varying ratios of CBD and THC (a ratio of 1:1 is often recommended as ideal for skin application). The skin has the highest amount and concentration of CB2 receptors in the body.
Hemp CBD is completely different from cannabis CBD. Hemp also derives from the Cannabis sativa L plant, and while it also contains THC, it contains it in volumes that are less than 0.3% by dry weight. Some governments, including the US, regulate the concentration of THC and permit a specific variety of hemp (called industrial hemp) that is bred with an especially low THC content. This is the reason why, when you type into Google “CBD oil for Sale”, you get hundreds of companies trying to sell you their products – according to most all of them, CBD oil from industrial hemp is 100% legal to sell online and ship to all 50 states.
During my visit, Penny showed me how she administers Harper’s CBD oils. We stood in her kitchen, where a window opened onto a vista of green grass and a wooden swing set out back. After carefully mixing and measuring Harper’s oils, Penny poured the liquid into a jumbo-sized plastic syringe. “We put this all online,” she told me, referring to the several YouTube videos she has made to help other parents administer hemp oil. Penny leaned down over her daughter to fit the tip of the syringe into her gastronomy tube, and I stood by silently. Harper looked at Penny, and Penny smiled back at her, and eased the plunger down.
CBD Isolates/Concentrates: Anyone familiar with smoking hash or other cannabis concentrates like wax and BHO will be no stranger to this delivery method. Simply sprinkle some into a vaporizer or water pipe, ignite, inhale, and enjoy! We find that this option is useful for individuals looking to elevate their regular consumption of CBD-rich cannabis flowers or other smokable herbs.
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Medical Disclaimer: Statements in any video or written content on this site have not been evaluated by the FDA. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. Representations regarding the efficacy and safety of CBD oil have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. The material on this site is provided for informational purposes only and is not medical advice. Always consult your physician before beginning any supplement program.
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