A rarely discussed health benefit of CBD oil is how it can reduce the risk of developing diabetes. In a study published in Neuropharmacology, researchers set out to explore what effect CBD would have on non-obese diabetes-prone female mice. Only 32 percent of the mice that received the CBD were diagnosed with diabetes, compared to 100 percent of the untreated group.
But all was not well. Harper has continued to experience health issues related to her condition. And seven months after starting to use CBD oil, Harper’s seizures returned— although not as frequently as before. Penny uses eleven iPhone reminders to keep track of Harper’s daily regimen of medications and food, and she records all of Harper’s seizures in a thickly bound black book. But as her parents continue to closely monitor Harper’s health and adjust her medications accordingly, her doctors are tightly limited in the advice they can offer when it comes to CBD oil. “There’s no research on this product, so they don’t say it’s good or bad. They just say, ‘Don’t stop giving it,’” Penny told me.
A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders.[64][65] Since then, 16 states have passed laws to allow the use of CBD products (not exceeding a specified concentration of THC) for the treatment of certain medical conditions.[66] This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content.[66] Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.[66]

Important note: Though CBD oil on its own is very safe, it may interact with medications, particularly opioids. Speak with your doctor if you’re concerned about interactions or are unsure about using hemp oil for your conditions. I know it’s tough to find a primary care doctor who understands alternative practices, but there are options like this service that pair you with a doctor who fits your lifestyle.
The body of research on cannabidiol, CBD oil benefits, THC, and other cannabinoids has grown exponentially in the past decade. The following brings together the latest scientific studies and stories from patients and doctors with advice on treating specific symptoms. It also includes dosage suggestions and information on recommended types of cannabinoid-based medicines for the particular condition.
Both varieties contain CBD and THC (albeit at different levels), which are the two primary compounds in the Cannabis sativa plant. The Cannabis plant is also very diverse, as it can grow in many different forms. The most common types are Sativa and Indica, but there are more, with each type having dozens – if not hundreds – of different adaptations and different ratios of active compounds, also known as cannabinoids.
My mother has dementia/Alzheimers along with a broken knee that they will not repair do to her mental status. She is currently in a nursing home. I firmly believe her mental situation began with the over use of hydrocodone for over 30 years and was acerbated by the trauma of breaking and disconnecting her knee cap. Since weaning her off of her meds (still in progress) we have regained much of her consciousness. I want to try CBD to help in her recovery or to help slow down the disease. I cannot find a dosage recommendation plus the nursing home/doctor does not recommend it. I would need to give it to her when I am there visiting (about 3 - 4 times per week). Is there a recommended dosage for dementia/Alzheimers?

Cannabinoid therapy is connected to the part of the biological matrix where body and brain meet. Since CBD (cannabidiol) and other compounds in cannabis are so similar to the chemicals created by our own bodies, they are integrated better than many synthetic drugs. According to Bradley E. Alger, a leading scientist in the study of endocannabinoids with a PhD from Harvard in experimental psychology, “With complex actions in our immune system, nervous system, and virtually all of the body’s organs, the endocannabinoids are literally a bridge between body and mind. By understanding this system, we begin to see a mechanism that could connect brain activity and states of physical health and disease.”[175]


CBD isolate will not show up on any drug test because it’s not made from the whole plant; traces of THC are within the legal limit & individual states are now passing laws to protect employees who are medical marijuana patients. It’s changing constantly & many states have patient advocacy groups that help new patients navigate the big learning curve.
CBD has been producing a whole lot of buzz in the health community of late – but perhaps not the kind of buzz you might expect from a cannabinoid. Since you’re reading this, you’ve probably heard of CBD and its many touted benefits. From chronic pain to mental health, CBD has the potential to alleviate an astonishing number of ailments. But like many, you might be fuzzy on the details. Consider this your primer on all things CBD.
Jump up ^ Hayakawa K, Mishima K, Hazekawa M, Sano K, Irie K, Orito K, Egawa T, Kitamura Y, Uchida N, Nishimura R, Egashira N, Iwasaki K, Fujiwara M (January 2008). "Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB(1) receptor-dependent mechanism". Brain Research. 1188: 157–64. doi:10.1016/j.brainres.2007.09.090. PMID 18021759.

In June 2018, following the FDA approval of Epidiolex for rare types of childhood epilepsy, Epidiolex was rescheduled as a Schedule V drug allowing its legal use as a pharmaceutical drug.[11] This change applies only to FDA-approved products containing no more than 0.1 percent THC.[63] This allows GW Pharma to sell Epidiolex, but it does not apply broadly and all other CBD-containing products remain Schedule I drugs.[63]

For kids with severe forms of epilepsy, changes in medication levels can be extremely dangerous. “If their levels go low, they’re at increased risk of seizures, which could lead to an emergency room visit or an ICU stay,” Knupp said. “On the other hand, if their levels go high, their side effects can increase dramatically.” Side effects from epilepsy medications can range anywhere from drowsiness to vomiting to heart arrhythmia, Knupp noted. “For some people that could mean a minor inconvenience, but for some patients it could be life-threatening.”
A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders.[64][65] Since then, 16 states have passed laws to allow the use of CBD products (not exceeding a specified concentration of THC) for the treatment of certain medical conditions.[66] This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content.[66] Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.[66]
Whether you’re purchasing CBD oil or CBD hemp oil for sale, remember that what is written on the bottle – the big 300mg – doesn’t mean that the 300mg is packed with CBD only. It means that the whole bottle is 300mg. It’s important to read the label. When calculating the actual CBD content, you’ll want to remember that the following ground rules apply:
CBD oil is at the leading edge of cannabis related health care. It is a new field where there are new players popping up daily. You may be desperate to try CBD oil and see if it can be beneficial to alleviate symptoms you are feeling. However, the Internet can be like the old Wild West when it comes to making purchases. There are always going to be companies that won’t live up to expectations; however, there are reputable companies interested in your health and making sure you get the kind of CBD oil that will help you. You ask where to buy CBD oil online, but you really want to know where you can get a safe product that works.
Hi Marilyn, I would recommend a topical lotion or salve to start for instant relief.. Maybe 250 to 300 mg tincture to see how you feel. For me, the salve took the pain in my hands away in under a minute. I didn't notice how much the tincture worked until I forgot to take on vacation. Pain that was pretty much gone but came back, I was tired, grumpy and felt horrible. It works, just need to find right product and dosage for you.
For example, using CBD vape oil requires a vaporizer, something you may be unfamiliar with, and for a beginner it can be intimidating. But vaping is only one option, and if you’re new to the world of CBD, a tincture is your best bet—it’s portable, discreet, and easy to use. And with only a few drops or sprays on your tongue, it’s super easy to keep track of your daily serving size.
CBD Oil, derived from agricultural hemp, has been widely recognized for its many benefits on human health. It has grown in popularity amongst the medical community as a key supplement for maintaining homeostasis. Because CBD oil has the ability to talk to nearly every organ system in the body via the Endocannabinoid System (ECS) this plant-based nutrient plays a key role in optimizing balance and enhancing quality of life.
I just started taking CBD oil , I am on my 2nd Hip replacement surgery due to device failures looking at a 3rd surgery. Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.

Correct Answer: Each batch of flower AND finished product should be tested by a state certified testing facility for potency, legality and safety. These test results should also be made available to any patient that requests them. These tests should certify 3 things: the amount of CBD contained in the product, the amount of THC in the product (the starting hemp plant material must test below 0.3%), and the lack of mold or toxic pesticides.
It’s a truism to state that pain is an inevitable part of life. And it’s true that we all, from time to time, experience pain that is short-lived and treatable. But those who deal with chronic pain know the debilitating, life-sucking reality of this condition. And traditional medications often come with long lists of side effects which can be as debilitating as the pain itself.
This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.
Some industry insiders argue that organic, pharmaceutical-grade ethanol, which is a grain alcohol, is optimal and eliminates certain toxins and residues in the raw plant material itself. But others say that while this extraction method yields a high amount of cannabinoids and is GRAS (Generally Recognized as Safe) for human consumption, it destroys the plant’s waxes, leading to a less potent oil.

Phillip Hague, the chief horticulturist at a Denver cannabis company called Mindful, sniffs the roots of a plant to check on their health. He’s grown cannabis most of his life and has traveled the world researching its many varieties. He’s interested in developing new strains with higher concentrations of marijuana’s lesser known compounds that appear to have medical uses. “Cannabis speaks to me,” he says.
Cannabinoid therapy is connected to the part of the biological matrix where body and brain meet. Since CBD (cannabidiol) and other compounds in cannabis are so similar to the chemicals created by our own bodies, they are integrated better than many synthetic drugs. According to Bradley E. Alger, a leading scientist in the study of endocannabinoids with a PhD from Harvard in experimental psychology, “With complex actions in our immune system, nervous system, and virtually all of the body’s organs, the endocannabinoids are literally a bridge between body and mind. By understanding this system, we begin to see a mechanism that could connect brain activity and states of physical health and disease.”[175]
Research conducted by Vandrey and his colleagues has even shown that some CBD products contain significant levels of THC—which could get a child high and cause other unpleasant side effects. “This is an area that exists in a grey area of legality,” Vandrey says. “And because of that, anyone thinking about using cannabidiol, of any type, should proceed with caution.”

Look for what are known as “full-spectrum” CBD products. These products contain other compounds of the hemp plant in addition to CBD. It’s believed that the compounds work together to provide the claimed benefits, much as eating an orange is usually a better choice than drinking orange juice. One key exception is if you’re subject to workplace drug testing. A CBD isolate, in which the rest of the plant’s compounds are removed, should reduce the already tiny chance of trace amounts of THC being present.


HoneyColony and its materials are not intended to treat, diagnose, cure or prevent any disease. All material on HoneyColony is provided for educational purposes only. Always seek the advice of your physician or another qualified healthcare provider for any questions you have regarding a medical condition, and before undertaking any diet, exercise or other health related program.
Designed to provide the optimum absorption of CBD into the blood stream by employing a patented slow release delivery system. It’s well accepted that CBD is most effective when taken sublingualy, however most oils when taken in this way are swallowed and broken down by your body. The Gel-Tab™. is placed under the tongue and the CBD is slowly absorbed resulting in higher rates of CBD being absorbed than what would be achieved with a normal oil

In this review, the effects of cannabinoids in the regulation of the following endocrine systems are discussed: the hypothalamic-pituitary-gonadal axis and hypothalamic-pituitary-adrenal cortex axis. Cannabis users have reduced levels of gonadotropins, reduced prolactin and growth hormone. Cannabis affects corticotropin-releasing hormone-, thyrotropin-releasing hormone-, vasopressin-, and oxytocin-expressing neurons. Therefore, our findings reveal a mechanism of rapid glucocorticoid feedback inhibition of hypothalamic hormone secretion via endocannabinoid release in the paraventricular nucleus of the hypothalamus and provide a link between the actions of glucocorticoids and cannabinoids in the hypothalamus that regulate stress and energy homeostasis. Glucocorticoid negative feedback in the brain controls stress, feeding, and neural-immune interactions by regulating the hypothalamic-pituitary-adrenal axis. Cannabis increases dopamine which decreases prolactin. Cannabis decreases oxytocin, thyroid hormone and growth hormone, and disrupts the hypothalamic-pituitary-adrenal axis. Cannabinoids suppress fertility via reducing hypothalamic gonadotropin- releasing hormone output. γ-Aminobutyric acid (GABA)(A) receptor (GABA(A)-R)-mediated transmission is a major input to gonadotropin releasing hormone cells that can be excitatory. Cannabinoids act via inhibiting GABAergic input. Cannabis disregulates the hypothalamic-pituitary-adrenal axis circadian rhythm. Cannabis decreases serum concentrations of pituitary gonadotropins. Cannabis raises cortisol and ACTH which increases cortisol which uses up progesterone reducing testosterone and estrogen. Cannabis lowers testosterone in men by inhibiting testosterone secretion and impairs fertility in males through alteration in the testicular endocannabinoid system. Cannabis suppresses copulatory behavior even when testosterone levels are maintained. It decreases sperm concentration, causes defective sperm function or alteration of sperm morphology. Endocannabinoids control male reproduction acting at central and local level via cannabinoid receptors. The cannabinoid receptor CB1 has been characterized in the testis, in somatic and germ cells of mammalian and non-mammalian animal models, and its activity related to Leydig cell differentiation, steroidogenesis, spermiogenesis, sperm quality, and maturation. Testicular degeneration and necrosis is induced by chronic administration of cannabis. In both ovulating and menopausal women, cannabis can alter pituitary gonadotropin release and alter metabolism or target tissue response to gonadal steroids, leading to reduced estrogen and progesterone production and anovulatory menstrual cycles. Cannabis presents abnormal longer ovulatory cycle lengths in females. Cannabis suppresses luteinizing hormone when sex hormones are initially high, but, chronic cannabis lowers progesterone and testosterone in men, and lowers estrogen and progesterone in women, so luteinizing hormone significantly increases which raises night time core temperature for disrupted sleep. Cannabis increases hypothalamic nitric oxide which inhibits oxytocin. Cannabis is detrimental for lactating moms. Cannabis decreases maternal care, decreases aggressive instinctual behaviors for protection of young, suppresses maternal anxiolysis, decreases plasma oxytocin levels and milk consumption and decreases activation of oxytocinergic neurons in hypothalamic nuclei. Changes in the behavioral responses of lactating mothers treated with cannabis can be related to disruption in the neuroendocrine control of oxytocin secretion. Cannabis causes impairment of glucocorticoid feedback which either enhances or decreases performance on various tasks. Cannibis can cause a decrease in thyroid which negatively affects cerebellar development and motor performance involved in adult brain function. It induces consistent behavioral changes in adults, leading to severe anxiety and morphological changes in the hippocampus, however, it shows improvements for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side. Cannabis and Δ(9) -THC are anticonvulsant in most animal models but can be proconvulsant in some healthy animals. The simultaneous rapid stimulation of nitric oxide and endocannabinoid synthesis by glucocorticoids has important implications for the impact of stress on the brain as well as on neural-immune interactions in the hypothalamus. Cannabis has implications for psychosis. There are blunted psychotomimetic and amnestic effects with cannabis. Lithium increases oxytocin and helps in cannabis withdrawal, and pregnenolone/progesterone help in cannabis withdrawal as estrogen generally increases and progesterone decreases sensitivity to marijuana.


I’m glad so many of you have been helped; I tried it upon recommendation from accupuncturist to help with anxiety & funny mood in the afternoon. The first night I woke up in the middle of the night and couldn’t get back to sleep, and had the most horrible constant headache for the 3 days after I took it (and I hadn’t had a headache in months). Also had the anxiety/funny mood all day long. And burning eyes.
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Finally, most of the products below simply contain hemp oil extract, mixed with a neutral carrier oil like hemp seed oil or coconut oil. While hemp seed oil is packed with nutrition, CBD brands are beginning to offer supplements with added ingredients that may offer additional benefits. We’ve included the complete ingredients of every product. Be sure to avoid any known allergies and investigate the pros and cons of any additional ingredients.
CBD tinctures are some of the best all around CBD products! It’s hard to beat the convenience of having a few drops from a tincture as part of your morning routine, or taking the travel size with you on the go to use at your discretion. Looking for something more convenient and more effective? Check out our Full Line of CBD Capsules, Vape Pens and CBD Balms and Lotions
The seizures started in May 2013 when she was six months old. Infantile spasms, they were called. It looked like a startle reflex—her arms rigid at her side, her face a frozen mask of fear, her eyes fluttering from side to side. Addelyn Patrick’s little brain raced and surged, as though an electromagnetic storm were sweeping through it. “It’s your worst possible nightmare,” her mother, Meagan, says. “Just awful, awful, awful to watch your child in pain, in fear, and there’s nothing you can do to stop it.”
CBD has been shown to interact with the body’s endocannabinoid system, a network in the brain that seems to play a role in social behavior, circadian rhythm, and reward processing—all of which can be atypical in people with autism. For that reason, researchers are excited about a study that’s currently underway at the University of California San Diego about CBD’s potential as an autism therapy.
After Legalization of medical use of CBD, It will become the prime focus. Various different CBD products, Specially CBD Oil is in more demand. CBD Oil contains Hemp seed oil and Kosher-Grade Vegetable Glycerin. CBD Oil Can help to cure Anxiety, Alzheimer, Insomnia, Parkinsons’ disease and many more diseases. CBD Oil Can use as a best pain controller.
Phillip Hague, the chief horticulturist at a Denver cannabis company called Mindful, sniffs the roots of a plant to check on their health. He’s grown cannabis most of his life and has traveled the world researching its many varieties. He’s interested in developing new strains with higher concentrations of marijuana’s lesser known compounds that appear to have medical uses. “Cannabis speaks to me,” he says.
Disclaimer: These products are not for use by or sale to persons under the legal for where you live. These products should be used only as directed on the label. They should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. These product are not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited By Law.  Legal in all 50 states.  THC is under 0.3%.
All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).
On the federal level, several bills currently before Congress seek to change the way the government treats CBD. One such bill, the Compassionate Access Act, would exclude CBD from the classification of “marijuana” and remove both from the DEA’s list of Schedule I controlled substances. Rescheduling CBD in such a way would make research and cultivation of CBD much easier.
The most appropriate way of consuming CBD oil may be by placing few drops of it under your tongue. If you fear overdosing it, you may then consume the drops by placing them on your hand and then licking them. To avoid the unpleasant taste, add the oil drops in your sandwich. It is always advised to shake the tincture well before use. Before swallowing the CBD oil drops, let it remain in your mouth for about 60 seconds so that it gets absorbed in your system.
This one isn’t for beginners. Make no mistake, this is strong stuff. You will only need the size of a grain of rice taken once or twice daily (the equivalent of roughly 4.1 milligrams of CBD) to feel the desired effects. With that kind of serving size, the three-gram tube will last you a few months of daily use, giving you plenty of CBD goodness. This product is also available in one-gram and ten-gram tubes, along with a six-pack of ten-gram tubes.
Correct Answer: Ingestible CBD oil should be comprised of coconut MCT oil and full spectrum hemp extract (the part that contains the actual CBD). It’s important that the carrier oil contains Medium Chain Triglycerides (MCT), like coconut oil, because it is easier for the body to digest. Remember that cannabinoids are best delivered to the body in either fat or alcohol as a carrier.
Cannabis Oil: Cannabis oil is typically made from marijuana with a high THC percentage. Therefore, it must be purchased in an area where marijuana is legal or can be obtained with a prescription. The amounts of compounds, including CBD and THC, will drastically vary from product to product. Commercially produced cannabis oils will have more controlled concentrations of CBD and THC for medical purposes.

CBD oil promotes more restful sleep, and, according to research, is a potential treatment for sleep disorders. Obviously, showing up at work in a well-rested state allows for higher levels of productivity, lowered stress and a greater sense of well-being overall. This benefit can be particularly useful for those with unusual, irregular or nighttime work schedules.


...with due respect, your experience Locsta is almost precisely what happened with my....chihuahua. Degenerative disc disease, excruciating pain, prednisone worked, but couldn't keep her on it..pain killers and muscle relaxants didn't help, really thought I would have to put her down. Chi bloggers suggested CBD; gave PetReleaf a shot--like you, literally within minutes I could see the difference, in days she was pain free and now is back in charge of our world. The real key here is that with my dog, there is zero, nada, chance that there was any placebo effect...

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Medical Disclaimer: Statements in any video or written content on this site have not been evaluated by the FDA. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. Representations regarding the efficacy and safety of CBD oil have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. The material on this site is provided for informational purposes only and is not medical advice. Always consult your physician before beginning any supplement program.

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CBD Oil helps my pain. I use it daily. Watch the video below to learn more.

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