In studying over 4,600 test subjects, researchers found that current cannabis users had fasting insulin levels that were up to 16 percent lower than their non-using counterparts, higher levels of HDL cholesterol that protects against diabetes, and 17 percent lower levels of insulin resistance. Respondents who had used cannabis in their lifetime but were not current users showed similar but less pronounced associations, indicating that the protective effect of cannabis fades with time.[180]


CBD also encourages the body to convert white fat to brown fat. White fat is the kind of fat we typically think of when we think about body fat. Brown fat is fat that is in small deposits that behaves differently than white fat. Brown fat is said to improve health by enhancing the bodies ability to burn white fat, create heat, and even regulate blood sugar.
For immediate medicinal effects, vaporizing or smoking work well. This can be helpful for either initial sleep onset or for wakefulness in the middle of a rest period but only lasts one to three hours. The medication effect is immediate, whereas most ingested products take thirty to sixty minutes before taking effect (faster on an empty stomach) and last six to eight hours. Vaporizers that use a cartridge filled with the CO2 concentrate are convenient and highly effective, and these are available in various ratios of CBD to THC. Herbal vaporizers that use the whole plant are also an effective delivery method. Sublingual sprays or tinctures taken as liquid drops also take effect quickly and last longer than inhaled products.

“The need for enhanced bioavailability of the CBD phytonutrient is paramount”, adds Moriarity, “but tricky to accomplish without synthetic chemicals.” Most CBD products do not offer any bioavailability optimization, so 90 percent of the CBD is lost to first-pass effect, a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches systemic circulation.
After Legalization of medical use of CBD, It will become the prime focus. Various different CBD products, Specially CBD Oil is in more demand. CBD Oil contains Hemp seed oil and Kosher-Grade Vegetable Glycerin. CBD Oil Can help to cure Anxiety, Alzheimer, Insomnia, Parkinsons’ disease and many more diseases. CBD Oil Can use as a best pain controller.
This is a good but tricky question. Every person will need to find out for themselves how much CBD to take. There is no one-answer-fits-all. The response to how much CBD should I take is subjective. This is because it depends on what you are hoping for the outcome to be. If it is for general health, the amount of CBD mg will be less than if you are trying to deal with an issue.
Topical solutions also vary greatly in potency. For example, Prevail Botanical’s salve contains 1,000 milligrams of CBD in 2.2 ounces. Floyd’s of Leadville cream has 700 milligrams in a 30-gram (1.05 ounce) container. These deliver higher amounts of CBD than other topicals I tried, such as PlusCBD’s balm (100 milligrams in 1.3 ounces) and Medterra’s cream (750 milligrams in 3.4 ounces). Remember, more isn’t necessarily better.
"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia.

I appreciate your efforts in writing this article & don’t mean to disparage you, but there’s so much information that goes into this discussion & people need to be prepared ahead of time. One very important note is to make sure that nothing in the CBD will be contraindicated with many prescription medications, especially for diabetes, hypertension, blood thinners & anti-platelets for example. If a company’s website says their formula is a “proprietary blend”, call before you buy, please!


The CBD oil needs to be taken twice a day everyday. The dosage depends on symptoms and it takes 30 days to awken your natural cannabis system after you begin taking the oil. I personally use Hemp works CBD oil in the 750 strength and only need 5 drops sublingual 2 times daily and results are many. Problem with oil and alz.patients is getting them to hold oil under tongue for 60 seconds. We have just began to get my dad on it. He too is in a nursing home in the state of florida and they cannot deny him any medication my mom has requested that he receive. If she is not their they are supposed to administer and she will call them to make sure he gets it. He is not 30 days into dosing yet so I don't have any results to speak of. I do know that since he has started he has had no more bladder infection and has not fallen in 3 weeks. That's a record for him so we will continue to monitor. Best of luck to you and a lot is going to depend on the state your mom is in and what the state laws are concerning her rights or the rights of whom has her medical power of attorney
A sketchy outline of the cannabis genome already exists, but it’s highly fragmented, scattered into about 60,000 pieces. Kane’s ambitious goal, which will take many years to achieve, is to assemble those fragments in the right order. “The analogy I use is, we have 60,000 pages of what promises to be an excellent book, but they’re strewn all over the floor,” he says. “We have no idea yet how those pages fit together to make a good story.”
I love remedies that have many uses (like emu oil), and cannabidiol oil (or CBD or hemp oil) is gaining popularity for this reason. This oil extracted from the hemp plant has come under a lot of legal and moral questions. Opinions may differ but what can’t be ignored is the incredible healing power CBD oil seems to possess and how versatile it is as a supplement and natural remedy.

CBD isolate will not show up on any drug test because it’s not made from the whole plant; traces of THC are within the legal limit & individual states are now passing laws to protect employees who are medical marijuana patients. It’s changing constantly & many states have patient advocacy groups that help new patients navigate the big learning curve.
Always start with the micro dose to test sensitivity and go up as needed within the dosing range, before going to the next, until symptoms subside. The micro to standard dose is usually recommended to treat stress and anxiety with CBD. For relief of immediate symptoms, as in a panic or anxiety attack, vaporizing or smoking work well. The medication lasts one to three hours, whereas most ingested products, including CBD oil, take thirty to sixty minutes before taking effect and last six to eight hours. Vaporizers that use a cartridge filled with the CO2 concentrate are highly effective, and these are available in various ratios of CBD to THC. Herbal vaporizers that use the whole plant are also an effective delivery method. Sublingual sprays or tinctures taken as liquid drops take effect quickly and last longer than inhaled products.

We are staunch advocates of CBD and its many, amazing, scientifically-backed uses. We are also staunch advocates of our patrons and their access to the highest quality, 100% organic CBD products around. Getting the information you need, the exact product you want, and a no hassle transaction with no attached shipping charges – that’s what we are all about.
CBD oil contains significant amounts of substances important to human health so knowing the ingredients is the first step to buying CBD oil. Now you need to know what to look for when buying CBD oil online. You want to know the concentration of CBD oil in the product, whether there are any additives in the CBD oil or hemp oil, the type of product best suited to your needs (such as choosing between a capsule or topical) and the reputation of the brand.
When extracting THC from the cannabis plant, it’s not easy to separate the THC from the mixture. This requires skill, expertise, and technology. Some shady brands create DIY CBD oils by using dangerous solvents, and then try to sell their products online. They sell them at extremely low prices, looking to make a quick buck. Before purchasing, always make sure that the CBD oil you are looking at has no psychoactive effects, and makes sure that it has been extracted with CO2 techniques as this ensures that no dangerous chemical solvents were used. And remember that THC is illegal in most states, so you don’t want to get on the wrong side of the law.
CBD (Cannabidiol) is a naturally occurring compound found in the hemp plant (Cannabis Sativa). NuLeaf Naturals firmly believes that our organic CBD oil may improve the lives of individuals suffering from certain mental and physical ailments. The best of today’s science is on our side. A nonprofit called Project CBD has examined a wealth of peer-reviewed scientific research and concluded that cannabis oil may be therapeutic for individuals with conditions such as:
CBD also encourages the body to convert white fat to brown fat. White fat is the kind of fat we typically think of when we think about body fat. Brown fat is fat that is in small deposits that behaves differently than white fat. Brown fat is said to improve health by enhancing the bodies ability to burn white fat, create heat, and even regulate blood sugar.
Since opening the San Francisco office of Parsley Health in 2016, I’ve become exposed to the wide world of cannabis. I grew up in the midwest and had adopted conservative views of marijuana use. Despite living in California for almost two years, the first state to legalize medical marijuana in 1996, I was still skeptical of marijuana and CBD oil benefits. I was also hesitant to prescribe CBD to patients due to potential psychoactive effects when combined with THC and because it’s not a regulated substance. But as my patients at Parsley Health kept asking me about CBD, I decided to dig a little deeper into potential CBD oil benefits and was surprised at how promising it may be.
“CBD coupled with stretching, icing, and foam rolling is a common treatment plan for tendonitis injuries about the knee, such as iliotibial band syndrome,” says Charles Bush-Joseph, M.D., a professor of orthopedics at Rush University Medical Center in Chicago. “Many patients like the fact that CBD is a natural substance. While specific research on the use of CBD in this instance is lacking, many believe that it helps prevent muscle and collagen breakdown.”
The DEA isn’t the only government agency scrutinizing CBD vendors. To fend off the FDA, hemp oil companies contend their wares are not drugs but “dietary supplements.” Despite the suggestive “meds” in the company’s name, HempMedsPx is careful to note on its web site, “Although some of our founders are medical professionals, we cannot make medical claims about the benefits of our products.” Others are not quite so nuanced in their marketing. The internet is flooded with CBD products claiming to treat everything from seizures to arthritis to skin conditions and other maladies.
CBD & THC are just 2 of many cannabiniods that will be seen on certificates of analysis; CBN for example is known to treat insomnia due to it’s sedating qualities & the list of terpenes, is long & each one has it’s own specific medicinal value. There’s a tremendous amount of learning involved with finding the right CBD product as well as the individual doseage; it’s advised for all beginners to “start slow & low”.
Canabidol™ Oral Capsules deliver 100% Cannabis Sativa L. from specifically bred industrial hemp plants containing high potency Cannabidiol. Each CBD capsule contains all the Cannabinoids, terpenoids, essential oils and all the other compounds of the cannabis plant. A packet of 30 capsules contains 15,000mg of Cannabis Sativa L. and 300mg of CBD (Cannabidiol) Each capsule contains 500mg of Cannabis Sativa L. and 10mg of the active ingredient CBD
Designed to provide the optimum absorption of CBD into the blood stream by employing a patented slow release delivery system. It’s well accepted that CBD is most effective when taken sublingualy, however most oils when taken in this way are swallowed and broken down by your body. The Gel-Tab™. is placed under the tongue and the CBD is slowly absorbed resulting in higher rates of CBD being absorbed than what would be achieved with a normal oil
Agreed with Joe. CBD is best to treat anxiety, depression, pain, chronic pain, inflammation, Alzheimer’s and many more diseases. I’ve experienced good qualities of CBD. I was suffering from the chronic pain for a very long time. One of my friends suggested me to take CBD oil which can treat my pain. I took it for a few weeks twice a day and the pain was totally gone. I felt more relaxed and calm than ever before. I love CBD and I recommend it to people.
In order to convince people to buy CBD oil or other products made of hemp or containing cannabidiol, companies claim that their CBD can cure pretty much anything from cancer to acne scars, yet they have no scientific argument to back up their statements. It’s therefore not surprising to see that people are reluctant when it comes to purchasing such products, or that they feel overwhelmed and have no idea how to buy CBD oil without getting scammed.
It is a strict violation of the Food and Drug Administration DSHEA guidelines to make medical claims about the efficacy of CBD products in the treatment of any medical condition or symptom. Although preliminary research has shown tremendous promise of CBD oil helping people in pretty remarkable ways, legitimate CBD companies will refrain from making any direct medical claims. Be very wary of companies that defy this guideline, because if they disregard this particular rule, what other rules are they willing to ignore?
CBD is shorthand for cannabidiol, one of the more than 100 cannabinoids found in cannabis. CBD products are said to deliver their many claimed benefits by boosting the body’s endocannabinoid system, which is a system that “is a unique signaling pathway that controls the function of a variety of systems throughout the body, including the cardiovascular system,” says Nicholas DiPatrizio, Ph.D., a professor of biomedical sciences at the University of California, Riverside School of Medicine. (More on the endocannabinoid system later.)
If he had his way, what Mechoulam regards as the often irresponsible silliness of recreational pot culture would give way to an earnest and enthusiastic embrace of cannabis—but only as a medical substance to be strictly regulated and relentlessly researched. “Right now,” he complains, “people don’t know what they’re getting. For it to work in the medical world, it has to be quantitative. If you can’t count it, it’s not science.”

Cannabinoids can be used along with opioid medications, and a number of studies have demonstrated that they can reduce the amount of opioids needed, lessen the buildup of tolerance, and reduce the severity of withdrawal.[384] At least ten randomized, controlled trials on over one thousand patients have demonstrated efficacy of cannabinoids for neuropathic pain of various origins.

Hi I've had rsd over 25 years now and in stage 3 I take cbd I'mor nong 6 weeks now and it's helped tons w my depression,sleep,constipation as well as energy. I take 2 drops under tounge every morning and Rick spson oil 3 xs day.It's bern beyond life changing for me look into the rs oil w the cbd. It works.. I still take 1 opiad a day have taken 2 a day only 3 times in almost 2 months when I was in bad flare ..
To get almonds from an almond tree, you can just shake the tree. To get juice from an orange, you can simply squeeze the fruit. But getting CBD oil from hemp is a much more complicated process. The cheapest and easiest ways to extract CBD oil from hemp commonly involve harsh solvents that can leave chemical residue in the CBD oil. The best, and most reliable extraction method, uses carbon dioxide (CO2) under high pressure and extremely low temperatures to pull out as much CBD as possible without introducing contaminants. Once the CO2 is no longer under intense pressure, it simply evaporates, leaving virtually no trace of extraction on the CBD oil.
This is an amazing product! I have Ehlers Danlos type 3 & 4. I have been living with chronic pain since my early twenties. I am now 41 yrs old and can say that today, because of Rapid Releaf and their incredible people, I feel better than I have in a long time. After 31 surgeries for various skeletal problems(I have three total joint replacements)I just assumed my life would always include pain and anxiety medication. I called Rapid Releaf and was helped by Josh. He took as much time as I needed to explain their product and how he thought it could help me. Three days after starting the CBD oil regimen, I am almost completely off of the narcotics. I have stopped taking all of my anxiety meds( I took Xanax and Valium for almost 15 years) and am currently working a program designed specifically to my needs and situation. I have slept more and feel rested in the morning. I can’t say thank you enough for giving me a life back! No more every day doctor visits or trips to the pharmacy. I am living a life that I never dreamed could be mine. I am living a normal everyday life under extraordinary circumstances! Thank you for the time you have dedicated to me and my situation. I know I couldn’t be almost drug free within days of starting your program otherwise. It truly is a miracle to be able to go day to day, unrestricted by pain and the tie downs that come with prescription medications. I have more time and energy than I thought would be possible as I transition from a twenty year opiod dependent life, to one having nothing to hold me back.
Since pot increases alpha and theta sleep, it inhibits delta sleep, so it also inhibits growth hormone and klotho, the anti aging hormone. You may unknowingly be putting your body into a catabolic state speeding the destruction of your connective tissue and breaking down your connective tissue at a faster rate thus aging you faster, instead of building up stronger connective tissue which is your goal in getting healthy, normal, plus staying young.
Cannabidiol, also known as CBD, has risen dramatically in popularity as a treatment to reduce stress, and for good reason. It is available for internal use in many forms, including CBD oil, which is oil that contains a concentration of CBD. When placed and held under the tongue, CBD oil reaches the bloodstream quickly and begins offering benefits both relatively fast and, through consistent use, over time. Research is showing more and more ways CBD oil benefits the body by helping to reduce pain, resulting in a wide range of positive effects. These include the compound’s anti-inflammatory, neuroprotective, anti-epileptic, anti-anxiety and antipsychotic properties, although many users turn to the compound simply for everyday stress reduction without the mind-altering side effects of marijuana.

For most people with epilepsy, diagnosis sets off a gauntlet of trial-and-error attempts to find the right medication. The process is tortuous, with seizures alternately dying down and flaring up while side effects— fatigue, nausea, liver damage, and more—develop without warning. This is partly due to the fact that “epilepsy” is actually a broad category that includes a number of distinct seizure disorders. About 30 medications approved by the U.S. Food and Drug Administration are currently used to treat these conditions, and when a person first begins having seizures, there is often much tinkering with combinations and dosages. I spent years battling side effects like vomiting, dizziness, drowsiness, and severe headaches, which were alleviated only by yet another prescription medication. Parents who endure enough sleepless nights caring for a sick child can become desperate for a cure.


You’ll hear and read a lot about CBD products that can cure different forms of cancer and about hemp oil that has miraculously healed patients from anxiety, tumors, diabetes and whatnot. My advice? Beware of products whose benefits sound too good to be true. CBD oil is a powerful antioxidant whose strength is greater than that of vitamin C and E, and I’m sure we will soon have strong medical evidence for different health effects.

Medical reviews published in 2017 and 2018 incorporating numerous clinical trials concluded that cannabidiol is an effective treatment for certain types of childhood epilepsy.[18][19] An orally administered cannabidiol solution (brand name Epidiolex) was approved by the US Food and Drug Administration in June 2018 as a treatment for two rare forms of childhood epilepsy, Lennox-Gastaut syndrome and Dravet syndrome.[11]


Watch Out For: Hemp grown in the European Union (EU) and China. Even in countries with agricultural regulations, the list of approved pesticides is far from safe. Thus you are really relying on the specific company’s ethical standards when it comes to hemp cultivation. The reason this is such a big deal with hemp when compared to other plants, is that hemp is a dynamic accumulator plant. Dynamic accumulator is a term used to describe plants that gather minerals – both good and bad – from the surrounding soil and store them in its tissues. So if you’re growing a hemp plant with petroleum-based pesticides in soil that contains heavy metals…you’re inevitably going to have a hemp plant containing both toxic pesticides and heavy metals. This is why many people have poor experiences when first trying CBD – you buy your vegetables organically, why not your hemp? The presence of these toxins is not regulated by any agency and they will end up in your CBD oil if you don’t purchase from the correct company. We like Ambary Gardens because they ensure that all of their CBD products are produced from organically and sustainably grown hemp without the use of pesticides.
The CBD vaporizer category is pretty crowded, but this CBD Vape Shot Kit from Alternate Vape continues to win the hearts of our customers, even over more expensive versions. The device itself is small, portable, lightweight, convenient, and easy to use. Simply add your favorite flavor, screw on the top, and you’re ready to start vaping. It’s the ideal starter kit for beginners new to CBD vaping, and it comes with everything you need: one e-pen, one USB charger, and one pre-loaded CBD cartridge.
Although most states restrict the use of CBD products to certain medical conditions, manufacturers of CBD claim their products are derived from industrial hemp, and therefore legal for anyone to use.[67] A number of these manufacturers ship CBD products to all 50 states, which the federal government has so far not intervened in.[68][69] CBD is also openly sold in head shops, health food stores, chiropractor clinics, optometrist offices, doctors offices and pharmacies in some states where such sales have not been explicitly legalized.[67][70]
In general, indica varieties of THC appear to work best as a sleep aid for most people. However, a significant number of people find THC, even indica strains, will make the mind more active. For these people, CBD oil can benefit them and tends to work well, providing the relaxation and calm for the mental as well as the physical body. For these people, CBD taken at nighttime as part of a bedtime regime produces a restful sleep, not the alertness produced in the daytime. This bidirectional effect of CBD is the result of balancing the endocannabinoid system.
Typically, pharmaceutical companies making cannabis-based medicines have sought to isolate individual compounds from the plant. But Mechoulam strongly suspects that in some cases those chemicals would work much better in concert with other compounds found in marijuana. He calls this the entourage effect, and it’s just one of the many cannabis mysteries that he says require further study.
In his office, however, Hernandez was wary of the CBD boom. He advises well-meaning parents to think twice about voyaging into the world of over-the-counter hemp oil treatments, even if their circumstances are dire. “It’s a huge gimmick that a lot of companies are using,” Hernandez said. “You don’t know what you’re getting. ... There’s a major quality problem.”
Royal Queen Seeds CBD Oil offers a convenient, discreet and quick way to dose yourself with a bit of CBD, no matter your situation or where you are. All of our CBD oil is created using organically grown hemp sourced from right here in Europe, extracted using the latest CO² techniques. It means our oil is 100% natural, offering pure and strong CBD. All you need to do as drop you dose under your tongue or in your food, and away you go!
CBD & THC are just 2 of many cannabiniods that will be seen on certificates of analysis; CBN for example is known to treat insomnia due to it’s sedating qualities & the list of terpenes, is long & each one has it’s own specific medicinal value. There’s a tremendous amount of learning involved with finding the right CBD product as well as the individual doseage; it’s advised for all beginners to “start slow & low”.

At Denver’s LivWell, which has an enormous indoor growing operation, workers remove marijuana leaves before the buds are trimmed, keeping the plants destined for medical use separate from those for recreational use. After Colorado legalized marijuana, thousands of young people from all over the world flocked to the state to participate in the multimillion-dollar business phenomenon that’s been called the Green Rush.

As the brain ages, the creation of new neurons slows down significantly. In order to maintain brain health and prevent degenerative diseases, new cells need to be continuously created. A 2008 study showed that low doses of CBD- and THC-like cannabinoids encouraged the creation of new nerve cells in animal models, even in aging brains.[192] CBD also benefits the brain by helping to prevent other nerve-related diseases like neuropathy and Alzheimer’s disease.


Phillip Hague, the chief horticulturist at a Denver cannabis company called Mindful, sniffs the roots of a plant to check on their health. He’s grown cannabis most of his life and has traveled the world researching its many varieties. He’s interested in developing new strains with higher concentrations of marijuana’s lesser known compounds that appear to have medical uses. “Cannabis speaks to me,” he says.

CBD & THC are just 2 of many cannabiniods that will be seen on certificates of analysis; CBN for example is known to treat insomnia due to it’s sedating qualities & the list of terpenes, is long & each one has it’s own specific medicinal value. There’s a tremendous amount of learning involved with finding the right CBD product as well as the individual doseage; it’s advised for all beginners to “start slow & low”.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
Neurologists are skilled at predicting side effects and interactions between well-researched pharmaceuticals. But due to the dearth of reliable research about CBD, doctors like Hernandez and Knupp cannot guide their patients in its use. If there are adverse reactions, Penny will find out because Harper will suffer through them. She has had to figure out through trial and error how best to mix and measure Harper’s oils. The bottom line, Penny said, is simple: “We are the research.”
Of course, the easiest solution, advocates say, is for the federal government to legalize cannabis completely. If cannabis were legalized—the whole plant and all its extracts, no confusing singling-out of specific compounds or anatomical features—then U.S. drug companies would be able to carefully cultivate and research its medicinal properties, and submit their findings to regulatory bodies like the FDA for trials and approval.
CBD could potentially be as effective for pain relief as an opioid, but without the potential for deadly addiction. Dr. Solomon shared a self-report study he conducted at UC Berkeley last year, which tracked patients that were using opioids for pain relief. When subjects tried using cannabis in lieu of opioids, the majority "reported that cannabis provided relief on par with their other medications, but without the unwanted side effects." He noted that more research needs to be done, but all signs point to pain relief—which would lead to fewer opioid-related deaths.
At Denver’s LivWell, which has an enormous indoor growing operation, workers remove marijuana leaves before the buds are trimmed, keeping the plants destined for medical use separate from those for recreational use. After Colorado legalized marijuana, thousands of young people from all over the world flocked to the state to participate in the multimillion-dollar business phenomenon that’s been called the Green Rush.
CBD may help reduces REM behavior disorder in people with Parkinson’s disease. REM behavior disorder is a condition that causes people to act out physically during dreaming and REM sleep. Typically, during REM, the body is largely paralyzed, a state known as REM atonia. This immobilization keeps sleepers from reacting physically to their dreams. In REM behavior disorder, this paralysis doesn’t occur, leaving people free to move—which can lead to disruptive sleep and to injuring themselves or their sleeping partners. Cannabis may also work to reduce pain and improve sleep quality in people with Parkinson’s disease.

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Medical Disclaimer: Statements in any video or written content on this site have not been evaluated by the FDA. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. Representations regarding the efficacy and safety of CBD oil have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. The material on this site is provided for informational purposes only and is not medical advice. Always consult your physician before beginning any supplement program.

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